Visions By Brian Job Optometry, Gold Coast, QLD, Australia.
Br J Ophthalmol. 2011 May;95(5):694-8. doi: 10.1136/bjo.2009.175216. Epub 2010 Oct 7.
Inferior retinal detachment pathology can be difficult to manage due to inadequate tamponade with low specific gravity tamponade agents and the propensity for the development of proliferative vitreoretinopathy (PVR). We report the efficacy and adverse effects associated with the use of perfluorocarbon heavy liquid as a short-term tamponade in managing such pathologies.
Retrospective analysis of 17 eyes treated with short-term perfluoro-n-octane tamponade for complex inferior retinal pathology, including inferior detachment and PVR. Mean follow-up time was 14 months and mean tamponade duration was 7 days.
Reattachment of the retina during the study period was achieved with a single set of operations in 13/17 (76%) eyes, with four eyes requiring a subsequent set of vitreoretinal operations. Postoperative visual acuity (VA) was equal to or better than preoperative VA in 14 (82%) of 17 eyes. Complications arising during the follow-up period included superior redetachment, atrophic macular changes, minor macular haemorrhage, cataract, elevated intraocular pressure, corneal defects, PVR, epiretinal membrane and retained perfluorocarbon heavy liquid. One case of intraocular inflammation occurred >6 months after removal of perfluoro-n-octane tamponade.
Short-term perfluoro-n-octane tamponade achieved a stable reattachment rate of 76% when used to manage challenging retinal pathologies.
由于低比重的眼内填充剂不足以填塞以及易于发生增生性玻璃体视网膜病变（PVR），视网膜下的脱离病变难以处理。我们报告使用全氟碳重液作为短期眼内填充来治疗这些病变的疗效和不良反应。
对 17 只眼进行了回顾性分析，这些眼由于复杂的视网膜下病变，包括视网膜下脱离和 PVR，接受了短期全氟辛烷眼内填充。平均随访时间为 14 个月，平均填充时间为 7 天。
在研究期间，17 只眼中的 13 只（76%）通过单一手术组实现了视网膜复位，4 只眼需要进一步的玻璃体视网膜手术。在 17 只眼中，14 只（82%）术后视力与术前相同或更好。随访期间出现的并发症包括上方视网膜再脱离、萎缩性黄斑改变、小的黄斑出血、白内障、眼内压升高、角膜缺陷、PVR、视网膜内膜和残留全氟碳重液。1 例眼内炎症发生在全氟辛烷取出 >6 个月后。
在处理具有挑战性的视网膜病变时，短期全氟辛烷眼内填充的稳定复位率为 76%。
