Carme Bernard, Demar Magalie, Ajzenberg Daniel, Dardé Marie Laure
Université des Antilles et de la Guyane, Cayenne, French Guiana.
Emerg Infect Dis. 2009 Apr;15(4):656-8. doi: 10.3201/eid1504.081306.
From 1998 through 2006, 44 cases of severe primary toxoplasmosis were observed in French Guiana in immunocompetent adults. Toxoplasma gondii isolates exhibited an atypical multilocus genotype. Severe disease in humans may result from poor host adaptation to neotropical zoonotic strains of T. gondii circulating in a forest-based cycle.
1998年至2006年期间,在法属圭亚那观察到44例免疫功能正常的成年人患严重原发性弓形虫病。弓形虫分离株表现出非典型的多位点基因型。人类的严重疾病可能是由于宿主对在森林循环中传播的新热带地区人畜共患弓形虫菌株适应不良所致。