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[人类视觉皮层V5区功能连接网络的变化:一项功能磁共振成像研究]

[Changes of functional connectivity network of human V5 in visual cortex: a functional MRI study].

作者信息

Zheng Gang, Shao Xiaoli, Zhong Yuan, Zhou Jiemin, Zhang Zhiqing, Lu Guangming

机构信息

College of Civil Aviation, Nanjing University of Aeronautics and Astronautics, Nanjing, 210016, China.

出版信息

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2009 Feb;26(1):14-7, 41.

PMID:19334545
Abstract

Changes of functional connectivity network of human V5 in different brain activity was investigated by combining spatial independent component analysis with temporal correlation. First, V5 was localized by performing spatial independent component analysis on the data from block design visual motion runs; then low frequency correlations between V5 and other regions were computed in two steady states (resting state and the state with continuous visual motion stimulus) to detect the functional connectivity networks. The results of experiment indicated: The functional connectivity network of V5 was more extensive and was consistent with the known anatomical connectivity during rest; when subjects were viewing motion, the network was limited in the visual cortex, suggesting that V5 was acting in concert with a network specific to the visual motion processing task.

摘要

通过将空间独立成分分析与时间相关性相结合,研究了人类V5在不同脑活动中的功能连接网络变化。首先,对来自组块设计视觉运动实验的数据进行空间独立成分分析来定位V5;然后在两种稳定状态(静息状态和连续视觉运动刺激状态)下计算V5与其他区域之间的低频相关性,以检测功能连接网络。实验结果表明:V5的功能连接网络在静息时更广泛且与已知的解剖学连接一致;当受试者观看运动时,该网络局限于视觉皮层,这表明V5与特定于视觉运动处理任务的网络协同作用。

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