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特发性炎性肌病皮肤表现的分类与评估综述

Review of the classification and assessment of the cutaneous manifestations of the idiopathic inflammatory myopathies.

作者信息

Dugan Elizabeth M, Huber Adam M, Miller Frederick W, Rider Lisa G

机构信息

Division of Dermatology, Department of Medicine, Georgetown University Hospital, Washington, DC.

出版信息

Dermatol Online J. 2009 Feb 15;15(2):2.

PMID:19336019
Abstract

Adult and juvenile dermatomyositis, polymyositis and myositis overlapping with another connective tissue disease are rare systemic autoimmune diseases with a primary feature of weakness and muscle inflammation. Cutaneous findings specific to the underlying condition are present in many patients with these disorders. Some lesions are highly characteristic of the idiopathic inflammatory myopathies (IIM), especially in dermatomyositis. Some cutaneous findings are common but not specific to the IIM and others are less frequently observed in patients with these illnesses. Many of these manifestations also have different grades of disease activity or damage. This photoessay reviews the classification and assessment of the cutaneous manifestations of the IIM and presents example photographs of many of the lesions of adult and juvenile IIM accumulated from the clinical experience of international experts in these conditions. The purpose of this work is to facilitate better recognition of the diverse cutaneous manifestations associated with these inflammatory myopathies.

摘要

成人及青少年皮肌炎、多发性肌炎以及与其他结缔组织病重叠的肌炎是罕见的系统性自身免疫性疾病,其主要特征为肌无力和肌肉炎症。许多患有这些疾病的患者会出现与潜在病情相关的皮肤表现。一些皮损是特发性炎性肌病(IIM)的高度特征性表现,尤其是在皮肌炎中。一些皮肤表现较为常见,但并非IIM所特有,而其他一些则在这些疾病患者中较少见。这些表现中的许多也具有不同程度的疾病活动或损害。这篇图片文章回顾了IIM皮肤表现的分类和评估,并展示了从这些疾病的国际专家临床经验中积累的许多成人及青少年IIM皮损的示例照片。这项工作的目的是促进更好地识别与这些炎性肌病相关的各种皮肤表现。

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