Unit of Child Neurology and Psychiatry, Department of Neuroscience, University of Rome Tor Vergata, Rome, Italy.
World J Biol Psychiatry. 2009;10(4 Pt 2):495-502. doi: 10.1080/15622970902789148.
Attention deficit/hyperactivity disorder (ADHD) is the behavioural disorder most commonly diagnosed in childhood. In addition to the main symptoms of inattention, impulsiveness and hyperactivity, neurological soft signs (NSS) are often associated with ADHD. NSS are discrete motor and sensory disorders that cannot be linked to specific cerebral lesions. We review all the scientific contributions on NSS in ADHD. The conclusions support the presence of an alteration in the neural networks for motor control inhibition, at the base of the pathophysiology of NSS in children with ADHD, as well as a possible central role of dopamine in these neural circuits.
注意缺陷多动障碍（ADHD）是儿童中最常见的行为障碍。除了注意力不集中、冲动和多动等主要症状外，神经软体征（NSS）也常与 ADHD 相关。NSS 是离散的运动和感觉障碍，不能与特定的脑损伤联系起来。我们回顾了所有关于 ADHD 中 NSS 的科学贡献。这些结论支持了 ADHD 儿童的运动控制抑制神经网络存在改变的观点，这是 NSS 病理生理学的基础，同时也支持多巴胺在这些神经回路中可能发挥中心作用。
