Duncan Diane Irvine, Chubaty Roman
Aesthet Surg J. 2006 Sep-Oct;26(5):575-85. doi: 10.1016/j.asj.2006.08.006.
There is increasing interest in injection lipolysis as a technique for reducing small, localized fat deposits. While many articles have been published about injection lipolysis, none specifically address safety issues. A clinical safety data survey was sent to physicians practicing injection lipolysis. Seventy-five physicians from 17 countries responded. Data from the treatment of 17,376 patients who underwent a total of 56,320 injection sessions were analyzed. Among the topics reviewed in the survey were indications and contraindications for treatment, best and worst areas for treatment, and additives to the formula and their efficacy. Expected sequelae were differentiated from unexpected complications. The safety data collected here indicate that, when practiced by licensed and certified physicians, the safety record for injection lipolysis is excellent. There were no deaths or hospitalizations resulting from treatment. There were also no bacterial or atypical mycobacterial infections, no reports of skin loss or ulceration, and no episodes of dermatitis or chronic skin irritation. Among the 17,376 patients treated, 0.0021% experienced transient hyperpigmentation, 0.015% had persistent pain beyond 2 weeks posttreatment, 0.0003% had a late allergic reaction, and 0.00006% had a contour irregularity requiring additional injection treatment. Disappointment at a less-than-expected aesthetic result was expressed by 12.34% of patients. There was consensus among responding physicians on the need for pretreatment patient education regarding realistic expectations. This survey is a representative, not definitive, survey of treatment results that is intended to serve as a starting point for further development and improvement of injection lipolysis technique.
作为一种减少小面积局部脂肪堆积的技术，注射溶脂术越来越受到关注。尽管已经发表了许多关于注射溶脂术的文章，但没有一篇专门讨论安全问题。我们向从事注射溶脂术的医生发送了一份临床安全数据调查问卷。来自17个国家的75名医生做出了回应。对17376例患者接受的总共5632次注射治疗的数据进行了分析。调查中审查的主题包括治疗的适应症和禁忌症、最佳和最差治疗部位、配方中的添加剂及其疗效。预期的后遗症与意外并发症区分开来。此处收集的安全数据表明，由有执照和认证的医生实施时，注射溶脂术的安全记录非常出色。治疗未导致死亡或住院。也没有细菌或非典型分枝杆菌感染，没有皮肤损失或溃疡的报告，也没有皮炎或慢性皮肤刺激的情况。在17376例接受治疗的患者中，0.0021%出现短暂性色素沉着，0.015%在治疗后2周以上仍有持续性疼痛，0.0003%出现迟发性过敏反应，0.00006%出现需要额外注射治疗的轮廓不规则。12.34%的患者对美学效果低于预期表示失望。回复问卷的医生一致认为，需要对患者进行术前教育，使其对治疗效果有现实的期望。这项调查是对治疗结果的代表性而非权威性调查，旨在作为进一步发展和改进注射溶脂术的起点。
