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骨关节炎进展的放射学标志物。

Radiologic markers of osteoarthritis progression.

作者信息

Hunter David J, Le Graverand Marie-Pierre H, Eckstein Felix

机构信息

New England Baptist Hospital, Boston, Massachusetts 02120, USA.

出版信息

Curr Opin Rheumatol. 2009 Mar;21(2):110-7. doi: 10.1097/BOR.0b013e3283235add.

DOI:10.1097/BOR.0b013e3283235add
PMID:19339920
Abstract

PURPOSE OF REVIEW

To review radiographic and MRI developments in measuring osteoarthritis progression in the tibiofemoral compartment of the knee.

RECENT FINDINGS

Standardized techniques for measuring joint space width in the medial tibiofemoral compartment, using standardized radiographic protocols, have become accepted for quantifying changes in tibiofemoral in knee osteoarthritis. In addition, there is a significant body of supporting data on the longitudinal change in MRI-derived cartilage morphology (thickness, volume) as an end point to reflect osteoarthritis progression/cartilage loss.

SUMMARY

This review appraises the current methods of measurement of osteoarthritis progression and limitations with regards their interpretation and further development.

摘要

综述目的

回顾在测量膝关节胫股关节间骨关节炎进展方面的放射学和磁共振成像（MRI）进展。

最新发现

使用标准化放射学方案测量胫股内侧关节间隙宽度的标准化技术，已被认可用于量化膝关节骨关节炎中胫股关节的变化。此外，有大量支持性数据表明，磁共振成像衍生的软骨形态（厚度、体积）的纵向变化可作为反映骨关节炎进展/软骨丢失的终点。

总结

本综述评估了目前测量骨关节炎进展的方法及其在解释和进一步发展方面的局限性。

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