新型隐球菌半乳甘露聚糖的结构含有β-D-葡萄糖醛酸。
The structure of Cryptococcus neoformans galactoxylomannan contains beta-D-glucuronic acid.
作者信息
Heiss Christian, Klutts J Stacey, Wang Zhirui, Doering Tamara L, Azadi Parastoo
机构信息
Analytical Services/Complex Carbohydrate Research Center, University of Georgia, 315 Riverbend Road, Athens, GA 30602, USA.
出版信息
Carbohydr Res. 2009 May 12;344(7):915-20. doi: 10.1016/j.carres.2009.03.003. Epub 2009 Mar 10.
Abstract
The structure of galactoxylomannan, a capsular polysaccharide from the opportunistic yeast Cryptococcus neoformans, was re-examined by NMR spectroscopy and GC-MS. The residue that is 3-linked to the side chain galactose and was previously assigned as beta-D-xylose [Vaishnav, V. V.; Bacon, B. E.; O'Neill, M.; Cherniak, R. Carbohydr. Res.1998, 306, 315-330] was determined to be beta-D-glucuronic acid. A revised structure for this polymer is presented, along with a proposal that this compound be termed glucuronoxylomannogalactan (GXMGal).
摘要
通过核磁共振光谱法和气相色谱-质谱联用技术，对新型隐球菌（一种机会性酵母）的荚膜多糖半乳甘露聚糖的结构进行了重新研究。与侧链半乳糖以3-连接的残基，之前被指定为β-D-木糖[Vaishnav, V. V.; Bacon, B. E.; O'Neill, M.; Cherniak, R. Carbohydr. Res.1998, 306, 315 - 330]，现确定为β-D-葡萄糖醛酸。本文给出了该聚合物的修订结构，并提议将此化合物命名为葡萄糖醛酸木糖甘露半乳聚糖（GXMGal）。
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