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预测中华人民共和国北京市汉坦病毒感染风险。

Predicting the risk of hantavirus infection in Beijing, People's Republic of China.

作者信息

Zhang Wen-Yi, Fang Li-Qun, Jiang Jia-Fu, Hui Feng-Ming, Glass Gregory E, Yan Lei, Xu You-Fu, Zhao Wen-Juan, Yang Hong, Liu Wei, Cao Wu-Chun

机构信息

Beijing Institute of Microbiology and Epidemiology, Beijing, People's Republic of China.

出版信息

Am J Trop Med Hyg. 2009 Apr;80(4):678-83.

Abstract

To understand the spatial distribution of hantavirus infections across landscapes and its influencing environment factors in Beijing, People's Republic of China, rodents captured in this region were examined for hantavirus by reverse transcription-polymerase chain reaction. A total of 1,639 rodents were trapped at 86 randomly selected sites. The overall infection rate for hantavirus was 7.14% in the rodents. Multivariate logistic regression analysis indicated that the natural infection rates for hantavirus in rodents were significantly associated with rice agriculture (odds ratio [OR] = 2.88, 95% confidence interval [CI] = 1.27-30.70), orchards (OR = 1.12, 95% CI = 1.02-5.96), and moderate elevation (OR = 9.83, 95% CI = 2.22-43.55). A risk map was constructed on the basis of these significant factors to predict extension and transmission of infection with hantavirus in this region.

摘要

为了解中华人民共和国北京市汉坦病毒感染在不同景观中的空间分布及其影响环境因素,采用逆转录-聚合酶链反应对该地区捕获的啮齿动物进行汉坦病毒检测。在86个随机选择的地点共捕获1639只啮齿动物。啮齿动物中汉坦病毒的总体感染率为7.14%。多因素logistic回归分析表明,啮齿动物中汉坦病毒的自然感染率与水稻种植(比值比[OR]=2.88,95%置信区间[CI]=1.27-30.70)、果园(OR=1.12,95%CI=1.02-5.96)和中等海拔(OR=9.83,95%CI=2.22-43.55)显著相关。基于这些显著因素构建了风险地图,以预测该地区汉坦病毒感染的传播和扩散。

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