Department of Critical Care Medicine, Unit of Gerontology and Geriatric Medicine, University of Florence and Azienda Ospedaliero-Universitaria Careggi, Via delle Oblate 4, Florence, Italy.
J Gerontol A Biol Sci Med Sci. 2010 Feb;65(2):159-64. doi: 10.1093/gerona/glp043. Epub 2009 Apr 6.
Prognostic stratification of older patients with complex medical problems among those who access the emergency department (ED) may improve the effectiveness of geriatric interventions. Whether such targeting can be performed through simple administrative data is unknown.
We examined the discharge records for 10,913 patients aged 75 years or older admitted during 2005 to the ED of all public hospitals in Florence, Italy. Using information on demographics, drug treatment, previous hospital admissions, and discharge diagnoses, we developed a 1-year mortality prognostic index. The predictive validity of this index was tested in a subsample of patients independent of the subsample used for its original development. Finally, we tested whether patients stratified by the prognostic index had different mortality when admitted to a geriatrics compared with an internal medicine ward.
In the validation subsample, patients with scores of 4-6, 7-10, and 11+ compared with those with scores less than 4 had hazard ratios (95% confidence interval) for 1-year mortality of, respectively, 1.5 (1.3-1.7), 2.2 (1.3-1.7), and 3.0 (2.6-3.4). Patients in the worse prognostic stratum experienced 33% higher mortality when admitted to an internal medicine compared with a geriatrics ward, although mortality was not significantly affected by the type of ward of admission in all other risk strata.
Simple administrative data provide prognostic information on long-term mortality in older patients hospitalized via ED. Patients with worse prognostic index scores appear to benefit from admission in a geriatrics compared with an internal medicine ward.
在急诊科(ED)就诊的有复杂医疗问题的老年患者中进行预后分层,可能会提高老年干预措施的效果。尚不清楚是否可以通过简单的行政数据来实现这种针对性。
我们研究了意大利佛罗伦萨所有公立医院在 2005 年期间收治的 10913 名 75 岁或以上患者的出院记录。利用人口统计学、药物治疗、既往住院和出院诊断方面的信息,我们开发了一个 1 年死亡率预测指数。该指数的预测准确性在原始开发数据之外的患者子样本中进行了测试。最后,我们测试了根据预后指数分层的患者在入住老年科和内科病房时的死亡率是否不同。
在验证子样本中,与评分<4 的患者相比,评分 4-6、7-10 和 11+的患者的 1 年死亡率的风险比(95%置信区间)分别为 1.5(1.3-1.7)、2.2(1.3-1.7)和 3.0(2.6-3.4)。在预后较差的分层中,与入住老年科相比,患者入住内科的死亡率高 33%,但在所有其他风险分层中,入住科室类型对死亡率没有显著影响。
简单的行政数据提供了 ED 住院老年患者长期死亡率的预后信息。与入住内科相比,预后指数评分较差的患者似乎从入住老年科中受益。