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美国成年人身体活动与膀胱过度活动症之间的关系:一项基于2007 - 2018年美国国家健康与营养检查调查的横断面研究

The relationship between physical activity and overactive bladder among American adults: a cross-sectional study from NHANES 2007-2018.

作者信息

Wu Tianen, Xu Binbin

机构信息

Department of Urology, Jinjiang Municipal Hospital, Quanzhou, 362200, Fujian Province, China.

Department of Emergency, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, 362200, Fujian Province, China.

出版信息

Sci Rep. 2025 May 10;15(1):16280. doi: 10.1038/s41598-025-01272-z.

Abstract

This study aimed to explore the association between physical activity (PA) and the risk of Overactive Bladder (OAB) in American adults. This analysis comprises a cross-sectional study of comprehensive population data collected from the National Health and Nutrition Examination Surveys spanning the years 2007 to 2018. Adults were categorized into four PA patterns (inactive, insufficiently active, weekend warrior, and regularly active) based on self-reported PA levels. We employed a weighted logistic regression model, restricted cubic spline (RCS) analysis, and subgroup analyses to investigate the relationship between PA patterns and OAB. This research included 17,050 subjects. After thorough adjustments for covariates, multivariate logistic regression models revealed that weekend warrior, and regularly active adults had a reduced risk of OAB compared with inactive adults, with odds ratios (ORs) of 0.96 (95% CI 0.94, 0.98), and 0.97 (95% CI 0.95, 0.99), respectively. RCS analysis revealed a nonlinear relationship between total weekly PA duration (in minutes) and the incidence of OAB, with approximately 915.41 min of total PA duration (minutes per week) associated with the lowest risk of OAB. This study demonstrated that adults engaging in either the regularly active or weekend warrior patterns experienced a lower risk of OAB compared to inactive adults. PA could be considered as part of a broader strategy for OAB prevention.

摘要

本研究旨在探讨美国成年人身体活动(PA)与膀胱过度活动症(OAB)风险之间的关联。该分析包括一项横断面研究,其数据来自于2007年至2018年期间进行的全国健康与营养检查调查所收集的综合人群数据。根据自我报告的PA水平,成年人被分为四种PA模式(不活动、活动不足、周末战士型和经常活动型)。我们采用加权逻辑回归模型、受限立方样条(RCS)分析和亚组分析来研究PA模式与OAB之间的关系。本研究纳入了17,050名受试者。在对协变量进行充分调整后,多变量逻辑回归模型显示,与不活动的成年人相比,周末战士型和经常活动型的成年人患OAB的风险降低,优势比(OR)分别为0.96(95%置信区间0.94, 0.98)和0.97(95%置信区间0.95, 0.99)。RCS分析显示,每周总的PA时长(以分钟计)与OAB发病率之间存在非线性关系,总PA时长约为915.41分钟(每周分钟数)时OAB风险最低。本研究表明,与不活动的成年人相比,采用经常活动型或周末战士型模式的成年人患OAB的风险较低。PA可被视为OAB预防更广泛策略的一部分。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b8b/12065866/188fc24cdd6f/41598_2025_1272_Fig1_HTML.jpg

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