Miranda Samuel de Paula, Macedo Rafael Nogueira de, Silva Júnior Geraldo Bezerra da, Daher Elizabeth De Francesco
Universidade Federal do Ceará, Fortaleza, Brasil.
Rev Assoc Med Bras (1992). 2009 Jan-Feb;55(1):89-94. doi: 10.1590/s0104-42302009000100022.
Chronic kidney disease (CKD) is one of the most important problems of public health, worldwide. Anemia is frequent in CKD, affecting approximately 90% of patients. The relationship between anemia and cardiovascular disease is well established and is due to alterations in left ventricular structure and function. Anemia per se can lead to significant cardiac morbidity in the absence of renal disease and is an independent risk factor for cardiac complication in the patient with renal insufficiency. The present review evaluates the inter-relations between anemia, heart failure and renal disease, which were recently included in the so-called cardio-renal anemia syndrome.
慢性肾脏病（CKD）是全球最重要的公共卫生问题之一。贫血在CKD患者中很常见，约90%的患者受其影响。贫血与心血管疾病之间的关系已得到充分证实，这是由于左心室结构和功能的改变所致。贫血本身可在无肾脏疾病的情况下导致严重的心脏疾病，并且是肾功能不全患者发生心脏并发症的独立危险因素。本综述评估了贫血、心力衰竭和肾脏疾病之间的相互关系，这些关系最近被纳入所谓的“心肾贫血综合征”。
