N-亚硝基双（2-氧代丙基）胺经口给予仓鼠后的效应。
The effect of N-nitrosobis(2-oxopropyl)amine after oral administration to hamsters.
作者信息
Pour P, Althoff J
出版信息
Cancer Lett. 1977 May;2(6):323-6. doi: 10.1016/s0304-3835(77)80012-8.
PMID:193628
Abstract
Oral administration of N-nitrosobis(2-oxopropyl)amine (BOP) in drinking water to Syrian golden hamsters for 90 days resulted in a high incidence of intra- and extrahepatic bile duct neoplasms. Only a few pancreatic neoplasms and no lung and kidney tumors developed, in contrast to results obtained after subcutaneous BOP administration.
摘要
给叙利亚金仓鼠饮用含N-亚硝基双(2-氧代丙基)胺(BOP)的水90天，导致肝内和肝外胆管肿瘤的高发病率。与皮下注射BOP后的结果相反，仅出现了少数胰腺肿瘤，未发生肺和肾肿瘤。
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