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Absorption of micronized progesterone from a nonliquefying vaginal cream.

作者信息

Kimzey L M, Gumowski J, Merriam G R, Grimes G J, Nelson L M

机构信息

Nursing Department, National Institutes of Health, Bethesda, Maryland 20892.

出版信息

Fertil Steril. 1991 Nov;56(5):995-6.

PMID:1936339
Abstract

An improved delivery method to achieve sustained physiological P levels would be useful. Based on this single-dose pharmacokinetic study, micronized P prepared in a nonliquefying vaginal cream holds promise as a convenient method to achieve this goal with a single daily application.

摘要

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Clin Exp Reprod Med. 2020 Jun;47(2):147-152. doi: 10.5653/cerm.2019.03132. Epub 2020 Apr 22.
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Pharmacokinetic Properties of Three Forms of Vaginal Progesterone Administered in Either Single Or Multiple Dose Regimen in Healthy Post-menopausal Chinese Women.健康绝经后中国女性单剂量或多剂量方案使用三种形式阴道孕酮的药代动力学特性
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Comparison of intravaginal progesterone gel and intramuscular 17-α-hydroxyprogesterone caproate in luteal phase support.
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Exp Ther Med. 2013 Jun;5(6):1740-1744. doi: 10.3892/etm.2013.1049. Epub 2013 Apr 4.