Akira Shizuo
Laboratory of Host Defense, WPI Immunology Frontier Research Center, Osaka University, Suita, Japan.
Proc Jpn Acad Ser B Phys Biol Sci. 2009;85(4):143-56. doi: 10.2183/pjab.85.143.
Mammalian immune response can be divided into innate and acquired immunity. Furthermore, much evidence has demonstrated that activation of innate immunity is a prerequisite to induction of acquired immunity. This paradigm shift has changed our thinking on the pathogenesis and treatment of infections, immune diseases, allergy, and cancers.
哺乳动物的免疫反应可分为先天性免疫和获得性免疫。此外，大量证据表明，先天性免疫的激活是诱导获得性免疫的先决条件。这一范式转变改变了我们对感染、免疫疾病、过敏和癌症的发病机制及治疗的看法。
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