Strle Franc, Stanek Gerold
Curr Probl Dermatol. 2009;37:51-110. doi: 10.1159/000213070. Epub 2009 Apr 8.
Lyme borrelosis is a multi-systemic disease caused byBorrelia burgdorferisensu lato. A complete presentation of the disease is an extremely unusual oberservation, in which a skin lesion follows a tick bite, the lesion itself is followed by heart and nervous system involvement, and later on by arthritis; late involvement of the eye, nervous system, joints and skin may also occur. Information on the relative frequency of individual clinical manifestations of Lyme borreliosis is limited; however, the skin is most frequently involved and skin manifestations frequently represent clues for the diagnosis. The only sign that enables a reliable clinical diagnoisis of Lyme borreliosis is a typical erythema migrans. Laboratory confirmation of a borrelial infection is needed for all manifestations of Lyme borreliosis, with the exception of typical skin lesions.
莱姆病是一种由伯氏疏螺旋体复合群引起的多系统疾病。该病的完整表现极为罕见，先是蜱叮咬后出现皮肤病变，接着是心脏和神经系统受累，随后出现关节炎；眼部、神经系统、关节和皮肤的晚期受累也可能发生。关于莱姆病各个临床表现相对频率的信息有限；然而，皮肤最常受累，皮肤表现常常是诊断的线索。能够对莱姆病进行可靠临床诊断的唯一体征是典型的游走性红斑。除典型皮肤病变外，莱姆病的所有临床表现都需要实验室确诊伯氏疏螺旋体感染。
