Duncan Alexis E, Grant Julia D, Bucholz Kathleen Keenan, Madden Pamela A F, Heath Andrew C
Midwest Alcoholism Research Center, Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri 63110, USA.
J Stud Alcohol Drugs. 2009 May;70(3):458-66. doi: 10.15288/jsad.2009.70.458.
The aim of this study was to examine the relationships between body mass index (BMI) and alcohol use and misuse in young adulthood in a sample of black and white female twins.
Cox proportional hazards and logistic regression models were used to examine the relationships between BMI category and first alcohol use, current weekly alcohol use, and current weekly heavy episodic drinking in 3,514 (14.06% black) young adult female twins. Analyses were conducted separately in black and white women.
After adjusting for relevant covariates, in white women obesity was protective against alcohol use (hazard ratio = 0.83; 95% confidence interval [CI]: 0.73-0.93) and against weekly drinking (odds ratio [OR] = 0.36; 95% CI: 0.24-0.53) and weekly heavy episodic drinking (OR = 0.51; 95% CI: 0.31-0.82) among ever drinkers compared with women of ideal weight. Overweight women living with their parents were less likely to be weekly drinkers (OR = 0.31; 95% CI: 0.16-0.61), whereas overweight women who were not living with their parents were less likely to be weekly heavy episodic drinkers (OR = 0.51; 95% CI: 0.31-0.82). Among black women, obesity was not associated with any of the drinking outcomes; however, black women who were overweight and who reported that the majority of their friends were not weekly drinkers had greater odds of reporting weekly drinking than those of ideal weight (OR = 2.91; 95% CI: 1.33-6.39).
Obese white women were less likely to ever use alcohol, be weekly drinkers, or be weekly heavy episodic drinkers than their ideal-weight peers. Body weight may affect drinking behavior in young women, and this effect may differ by race. Future research is needed to identify mediators and moderators of this relationship as well as to explore racial differences in the effect of body weight on drinking behavior.
本研究旨在调查黑人和白人女性双胞胎样本中,成年早期体重指数(BMI)与饮酒及酒精滥用之间的关系。
采用Cox比例风险模型和逻辑回归模型,研究3514名(14.06%为黑人)成年女性双胞胎的BMI类别与首次饮酒、当前每周饮酒量以及当前每周大量饮酒之间的关系。分析分别在黑人和白人女性中进行。
在调整相关协变量后,与体重正常的女性相比,白人女性中肥胖对饮酒有保护作用(风险比=0.83;95%置信区间[CI]:0.73 - 0.93),对每周饮酒(优势比[OR]=0.36;95% CI:0.24 - 0.53)和每周大量饮酒(OR = 0.51;95% CI:0.31 - 0.82)也有保护作用。与父母同住的超重女性每周饮酒的可能性较小(OR = 0.31;95% CI:0.16 - 0.61),而不住在父母家的超重女性每周大量饮酒的可能性较小(OR = 0.51;95% CI:0.31 - 0.82)。在黑人女性中,肥胖与任何饮酒结果均无关联;然而,报告大多数朋友不每周饮酒的超重黑人女性每周饮酒的几率高于体重正常者(OR = 2.91;95% CI:1.33 - 6.39)。
肥胖的白人女性与体重正常的同龄人相比,饮酒、每周饮酒或每周大量饮酒的可能性较小。体重可能会影响年轻女性的饮酒行为,且这种影响可能因种族而异。未来需要开展研究,以确定这种关系的中介因素和调节因素,并探讨体重对饮酒行为影响的种族差异。