Schmahl G
Institute of Special Zoology and Parasitology, Ruhr University, Bochum, F.R.G.
Folia Parasitol (Praha). 1991;38(2):97-106.
Monogeneans which parasitize fish are still treated by bathing the fish in solutions of simple chemicals or staining dyes. In the early 1960s an insecticide, trichlorphon, replaced to a large extent the formerly used simple chemicals. Its success was greater specificity against monogeneans and other ectoparasites, and to its great tolerance by the fish. The fact that the number of important monogenean species (i.e. Pseudodactylogyrus anguillae, P. bini, Gyrodactylus salaris) which cannot be treated sufficiently with simple chemicals or even trichlorphon is increasing, led to the need for systemically acting, novel chemotherapeutics. In laboratory and small scale trials praziquantel, levamisole, mebendazole and toltrazuril have been tested for efficacy against a broad spectrum of monogenean species.
寄生于鱼类的单殖吸虫仍通过将鱼浸浴在简单化学药品或染色染料溶液中来进行治疗。在20世纪60年代早期，一种杀虫剂敌百虫在很大程度上取代了以前使用的简单化学药品。它的成功之处在于对单殖吸虫和其他体外寄生虫具有更高的特异性，以及鱼类对它的高度耐受性。由于无法用简单化学药品甚至敌百虫充分治疗的重要单殖吸虫种类（即鳗鲡伪指环虫、比氏伪指环虫、鲑三代虫）的数量在增加，因此需要有全身作用的新型化学治疗剂。在实验室和小规模试验中，已对吡喹酮、左旋咪唑、甲苯达唑和托曲珠利针对多种单殖吸虫种类的疗效进行了测试。
