HIV 阳性妇女的生育选择和管理。

Fertility choices and management for HIV-positive women.

机构信息

aDepartment of Maternal-Fetal Medicine. Institute Clinic of Gynecology, Obstetrics, and Neonatology, Hospital Clinic, University of Barcelona, IDIBAPS, Spain bEugin Clinic, Barcelona, Spain.

出版信息

Curr Opin HIV AIDS. 2008 Mar;3(2):186-92. doi: 10.1097/COH.0b013e3282f51219.

Abstract

PURPOSE OF REVIEW

It is becoming increasingly important to address the issue of reproductive counselling and management of HIV-infected individuals during their reproductive years. Sexual and reproductive health-related needs and aspirations are similar to those of uninfected individuals but some differences require specific attention, which are discussed in this review.

RECENT FINDINGS

Hormonal contraception should be used with caution in women on antiretroviral treatment. Its impact on both HIV infectivity and disease progression is still controversial. An intrauterine device can be considered for pregnancy prevention and pregnancy termination should be offered in safe conditions. HIV-infected women have a lower spontaneous fertility rate, which may persist after assisted reproduction. Data on safety of antiretroviral treatment during conception are reassuring. No clear association can be found between exposure to antiretrovirals and fetal abnormalities. Secondary prevention remains crucial and condom use remains a key method.

SUMMARY

Different topics related to fertility choices among HIV-infected patients should be addressed. Family planning methods and termination of pregnancy have specific aspects among infected individuals. When needed, medically assisted reproduction may be required and antiretroviral treatment should be adapted before conception. Secondary prevention has a key role in reducing newly acquired infections.

摘要

目的综述

在生育年龄段的 HIV 感染者中,解决生育咨询和管理问题变得越来越重要。HIV 感染者的性与生殖健康相关需求和愿望与未感染者相似,但仍有一些需要特别关注的差异,本文对此进行了讨论。

最近的发现

正在接受抗逆转录病毒治疗的女性应谨慎使用激素避孕。其对 HIV 感染性和疾病进展的影响仍存在争议。宫内节育器可用于避孕,应在安全条件下提供妊娠终止。HIV 感染者的自然生育能力较低,这种情况在辅助生殖后可能仍会持续。关于妊娠期间使用抗逆转录病毒治疗的安全性数据令人安心。接触抗逆转录病毒药物与胎儿畸形之间没有明确的关联。二级预防仍然至关重要,避孕套的使用仍然是主要方法。

总结

应解决 HIV 感染者生育选择的不同问题。在感染者中,计划生育方法和终止妊娠有其特定的方面。在需要时,可能需要医学辅助生殖,并且应在受孕前调整抗逆转录病毒治疗。二级预防在减少新感染方面起着关键作用。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索