Murphy J K, Stephens C, Hartley T, Das A K, Hughes G R, McKee P H
Department of Pathology, University of Leeds, UK.
Histopathology. 1991 Oct;19(4):329-36. doi: 10.1111/j.1365-2559.1991.tb00047.x.
Subacute cutaneous lupus erythematosus is an uncommon, non-scarring variant of lupus erythematosus which has received scant attention in the pathology literature. Its recognition as a distinct entity is important, as, although mild systemic features may be associated, there is characteristically a relative absence of life-threatening renal or central nervous systemic involvement. Subacute cutaneous lupus erythematosus may be clinically sub-divided into the more common annular and the rarer papulosquamous (psoriasiform) variants. A clinicopathological study of five cases of the annular variant is presented with a review of the literature. We highlight the histological and ultrastructural appearances. Discriminatory features from the other variants of lupus erythematosus and additional conditions with which it may be confused, including lichen planus and acute graft-versus-host disease, are discussed.
亚急性皮肤型红斑狼疮是一种不常见的、无瘢痕形成的红斑狼疮变体，在病理学文献中很少受到关注。将其识别为一种独特的疾病很重要，因为尽管可能伴有轻度全身症状，但特征性地相对缺乏危及生命的肾脏或中枢神经系统受累情况。亚急性皮肤型红斑狼疮在临床上可细分为较常见的环形和较罕见的丘疹鳞屑型（银屑病样）变体。本文报告了5例环形变体的临床病理研究并对文献进行了综述。我们重点介绍了组织学和超微结构表现。讨论了与其他红斑狼疮变体以及可能与之混淆的其他疾病（包括扁平苔藓和急性移植物抗宿主病）的鉴别特征。
