De Braekeleer M
SOREP, Université du Québec à Chicoutimi, Canada.
Hum Hered. 1991;41(3):141-6. doi: 10.1159/000153992.
Saguenay-Lac-St-Jean is a geographically isolated region located in northeastern Quebec. Opened to the white settlement in 1938, its immigrants mainly came from Charlevoix, another isolated region of Quebec. The prevalence and/or incidence of several autosomal dominant and recessive disorders are very high. The overall birth prevalence of the recessive disorders was calculated at 1/207 living births and the overall carrier rate at 1/7 inhabitants. This situation may be explained by migration and social factors.
萨格奈-拉克圣让是位于魁北克省东北部的一个地理上孤立的地区。1938年对白人定居者开放，其移民主要来自魁北克的另一个孤立地区沙勒沃伊。几种常染色体显性和隐性疾病的患病率和/或发病率非常高。隐性疾病的总体出生患病率经计算为每207例活产中有1例，总体携带者率为每7名居民中有1例。这种情况可能由移民和社会因素来解释。
