佐剂性关节炎大鼠嗜酸性粒细胞上的白细胞介素-2受体
Interleukin-2 receptors on rat eosinophils in adjuvant arthritis.
作者信息
Meacock S C, Brandon D R, Smith W
机构信息
Lilly Research Centre Limited, Eli Lilly & Co., Windlesham, Surrey, U.K.
出版信息
Immunology. 1991 Sep;74(1):169-71.
Abstract
Monoclonal antibodies specific for the interleukin-2 receptor (IL-2R) have been used to demonstrate by immunohistochemical methods the presence of IL-2R on eosinophils as well as on lymphocytes in lymphoid tissue taken from rats with adjuvant arthritis. Evidence is presented which suggests that the IL-2R on eosinophils may have been induced by the disease process.
摘要
针对白细胞介素-2受体（IL-2R）的单克隆抗体已被用于通过免疫组织化学方法证明，在取自佐剂性关节炎大鼠的淋巴组织中，嗜酸性粒细胞以及淋巴细胞上存在IL-2R。现有证据表明，嗜酸性粒细胞上的IL-2R可能是由疾病过程诱导产生的。
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