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2009年美国睑缘炎:基于调查的患病率及治疗情况

Blepharitis in the United States 2009: a survey-based perspective on prevalence and treatment.

作者信息

Lemp Michael A, Nichols Kelly K

机构信息

Department of Ophthalmology, George Washington University School of Medicine, Washington, DC, USA.

出版信息

Ocul Surf. 2009 Apr;7(2 Suppl):S1-S14. doi: 10.1016/s1542-0124(12)70620-1.

Abstract

ABSTRACT Like dry eye disease 15 years ago, blepharitis today is a poorly defined condition about which there is considerable misunderstanding. For a variety of reasons, there is little good data on either the prevalence of blepharitis or how eyecare practitioners currently treat it. The work reported herein consists of two recent studies: a telephone survey of a representative sample of the adult US population (n = 5,000) whose purpose was to discover the frequency of common ocular surface symptoms associated with blepharitis; and a study that queried a selected group of ophthalmologists (n = 120) and a similarly selected group of optometrists (n = 84) about the frequency of blepharitis in their practices, the existence comorbid conditions, and their management strategies. This data suggests that blepharitis symptoms are very common in the US population, with younger individuals reporting more, and more frequent, symptoms than older people, contrary to clinical dogma. Ophthalmologists and optometrists report that blepharitis is commonly seen in clinical practice in 37% and 47% of their patients, respectively, and it is widely agreed that meibomian gland dysfunction (MGD) is the most common cause of evaporative dry eye disease. In addition, management paradigms are shifting away from more traditional management with antibiotic ointment and warm compress therapy to prescription therapy for anterior and posterior blepharitis.

摘要

摘要 就像15年前的干眼症一样,如今睑缘炎也是一种定义不明确且存在诸多误解的病症。由于种种原因,关于睑缘炎的患病率以及眼科护理从业者目前如何治疗该病,几乎没有可靠的数据。本文所报告的工作包括两项近期研究:一项对美国成年人口代表性样本(n = 5000)的电话调查,其目的是发现与睑缘炎相关的常见眼表症状的发生频率;另一项研究则询问了一组选定的眼科医生(n = 120)和一组同样选定的验光师(n = 84),了解他们诊所中睑缘炎的发生频率、并存病症的情况以及他们的管理策略。这些数据表明,睑缘炎症状在美国人群中非常常见,与临床教条相反,年轻人报告的症状比老年人更多、更频繁。眼科医生和验光师报告称,他们的患者中分别有37%和47%在临床实践中常见睑缘炎,并且人们普遍认为睑板腺功能障碍(MGD)是蒸发型干眼症最常见的原因。此外,管理模式正从使用抗生素眼膏和热敷疗法等更传统的管理方式转向针对睑缘炎前后部的处方治疗。

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