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用于调强放射治疗(IMRT)和容积调强弧形治疗(VMAT)验证的Delta4模体评估。

Evaluation of the Delta4 phantom for IMRT and VMAT verification.

作者信息

Bedford James L, Lee Young K, Wai Philip, South Christopher P, Warrington Alan P

机构信息

Joint Department of Physics, The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, Downs Road, Sutton, Surrey SM2 5PT, UK.

出版信息

Phys Med Biol. 2009 May 7;54(9):N167-76. doi: 10.1088/0031-9155/54/9/N04. Epub 2009 Apr 21.

Abstract

The Delta(4) diode array phantom (Scandidos, Uppsala, Sweden) was evaluated for verification of segmental intensity-modulated radiation therapy (IMRT) and volumetric modulated arc therapy (VMAT) on an Elekta linear accelerator (Crawley UK). The device was tested for angular sensitivity by irradiating it from 36 different gantry angles, and the responses of the device to various step-and-shoot segment doses and dose rates were evaluated using an ionization chamber as a comparison. The phantom was then compared with ionization chamber and film results for two prostate and pelvic nodes IMRT plans, two head and neck IMRT plans and two lung VMAT plans. These plans were calculated using Pinnacle(3) (Philips Radiation Oncology Systems, Madison, WI). The uniformity of angular response was better than 0.5% over the range of gantry angles. The uniformity of response of the Delta(4) to different segment monitor units and dose rates was better than 0.5%. The assessment of the IMRT and VMAT plans showed that the Delta(4) measured a dose within 2.5% of the ionization chamber, and compared to film recorded a slightly larger region (range -2% to +7%) agreeing with the planned dose to within 3% and 3 mm. The Delta(4) is a complex device and requires careful benchmarking, but following the successful completion of these measurements, the Delta(4) has been introduced into clinical use.

摘要

对Delta(4)二极管阵列模体(瑞典乌普萨拉的Scandidos公司)进行了评估,以验证在英国克劳利的医科达直线加速器上进行的调强放射治疗(IMRT)和容积调强弧形治疗(VMAT)的节段性剂量。通过从36个不同的机架角度对该设备进行照射来测试其角度敏感性,并使用电离室作为对照评估该设备对各种静态调强放疗节段剂量和剂量率的响应。然后将该模体与两个前列腺和盆腔淋巴结IMRT计划、两个头颈部IMRT计划以及两个肺部VMAT计划的电离室和胶片结果进行比较。这些计划使用Pinnacle(3)(威斯康星州麦迪逊市飞利浦放射肿瘤系统公司)进行计算。在机架角度范围内,角度响应的均匀性优于0.5%。Delta(4)对不同节段监测单位和剂量率的响应均匀性优于0.5%。对IMRT和VMAT计划的评估表明,Delta(4)测量的剂量在电离室测量剂量的2.5%以内,与胶片相比,记录的区域略大(范围为-2%至+7%),与计划剂量的一致性在3%和3毫米以内。Delta(4)是一种复杂的设备,需要仔细进行基准测试,但在成功完成这些测量后,Delta(4)已投入临床使用。

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