Kolde G
Hautklinik, Universität Münster.
Hautarzt. 1991 Sep;42(9):589-92.
A 75-year-old female patient with neurological disturbances and numerous erythematous skin infiltrates is presented. Angioendotheliomatosis proliferans systematisata was diagnosed on histological detection of intravascular tumour cells in the cutaneous blood vessels. On immunohistochemistry and electron microscopy, the mononuclear tumour cells were identified as atypical B-lymphocytes. Our results provide further evidence that angioendotheliomatosis proliferans systematisata is a malignant angiotropic lymphoma with neurocutaneous manifestation.
报告了一名75岁患有神经功能障碍和大量皮肤红斑浸润的女性患者。通过对皮肤血管内肿瘤细胞进行组织学检测，诊断为系统性增殖性血管内皮瘤病。经免疫组织化学和电子显微镜检查，单核肿瘤细胞被鉴定为非典型B淋巴细胞。我们的结果进一步证明，系统性增殖性血管内皮瘤病是一种具有神经皮肤表现的恶性亲血管性淋巴瘤。
