同种异体间充质干细胞移植治疗多发性硬化症。
Allogeneic mesenchymal stem cells transplantation in treatment of multiple sclerosis.
作者信息
Liang J, Zhang H, Hua B, Wang H, Wang J, Han Z, Sun L
机构信息
Department of Immunology and Rheumatology, Drum Tower Hospital, Nanjing University Medical School, Nanjing 210008, P. R. China.
出版信息
Mult Scler. 2009 May;15(5):644-6. doi: 10.1177/1352458509104590.
PMID:19389752
Abstract
Multiple sclerosis (MS) is a chronic autoimmune disorder of the central nervous system. Umbilical cord derived mesenchymal stem cells are immunosuppressive. We transplanted mesenchymal stem cells in a patient with refractory progressive MS, and the disease course was stabilized after the transplantation. We postulate that mesenchymal stem cells have a potent immunosuppressive effect in vivo.
摘要
多发性硬化症（MS）是一种中枢神经系统的慢性自身免疫性疾病。脐带间充质干细胞具有免疫抑制作用。我们对一名难治性进展型MS患者进行了间充质干细胞移植，移植后疾病进程得到稳定。我们推测间充质干细胞在体内具有强大的免疫抑制作用。
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