跨越适应度低谷的进化速度。
The pace of evolution across fitness valleys.
作者信息
Gokhale Chaitanya S, Iwasa Yoh, Nowak Martin A, Traulsen Arne
机构信息
Max-Planck-Institute for Evolutionary Biology, August-Thienemann-Str. 2, 24306 Plön, Germany.
出版信息
J Theor Biol. 2009 Aug 7;259(3):613-20. doi: 10.1016/j.jtbi.2009.04.011. Epub 2009 Apr 24.
Abstract
How fast does a population evolve from one fitness peak to another? We study the dynamics of evolving, asexually reproducing populations in which a certain number of mutations jointly confer a fitness advantage. We consider the time until a population has evolved from one fitness peak to another one with a higher fitness. The order of mutations can either be fixed or random. If the order of mutations is fixed, then the population follows a metaphorical ridge, a single path. If the order of mutations is arbitrary, then there are many ways to evolve to the higher fitness state. We address the time required for fixation in such scenarios and study how it is affected by the order of mutations, the population size, the fitness values and the mutation rate.
摘要
一个种群从一个适应度峰值进化到另一个适应度峰值的速度有多快？我们研究了进行无性繁殖的进化种群的动态变化，在这些种群中，一定数量的突变共同赋予了适应优势。我们考虑一个种群从一个适应度峰值进化到另一个适应度更高的峰值所需的时间。突变的顺序可以是固定的，也可以是随机的。如果突变顺序是固定的，那么种群遵循一条隐喻的山脊，即一条单一的路径。如果突变顺序是任意的，那么有许多方式可以进化到更高的适应度状态。我们探讨了在这些情况下固定所需的时间，并研究它是如何受到突变顺序、种群大小、适应度值和突变率影响的。
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