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在加拿大安大略省,使用ONRAB诱饵的空中投放作为一种控制浣熊和条纹臭鼬狂犬病的策略。

Aerial distribution of ONRAB baits as a tactic to control rabies in raccoons and striped skunks in Ontario, Canada.

作者信息

Rosatte R C, Donovan D, Davies J C, Allan M, Bachmann P, Stevenson B, Sobey K, Brown L, Silver A, Bennett K, Buchanan T, Bruce L, Gibson M, Beresford A, Beath A, Fehlner-Gardiner C, Lawson K

机构信息

Ontario Ministry of Natural Resources, Trent University, Peterborough, Ontario K9J 7B8, Canada.

出版信息

J Wildl Dis. 2009 Apr;45(2):363-74. doi: 10.7589/0090-3558-45.2.363.

Abstract

During August 2006 and 2007, baits containing oral rabies vaccine, live adenovirus vector, known as ONRAB , were aerially distributed in SW Ontario, Canada. Bait acceptance during 2006 was 62 and 74% in raccoons (Procyon lotor) in areas baited at 150 baits/km(2) and 75 and 77% in plots baited at 300 baits/km(2). During 2007, bait acceptance for raccoons ranged between 59% and 80%, and 83% and 87%, in areas baited at 75 and 400 baits/km(2), respectively. Bait acceptance by skunks varied among plots (5-24%). Rabies virus-specific seroconversion during 2006 averaged 66 and 81% in raccoons in areas baited at 150 and 300 baits/km(2), respectively. During 2007, seroconversion by raccoons was 76 and 84% in areas baited at 75 and 400 baits/km(2), respectively. Seroconversion by skunks varied among plots (17-51%). Vaccine efficacy, as judged by the percentage of animals that consumed a bait and seroconverted, averaged 79 and 87% during 2006 for raccoons in areas baited at 150 and 300 baits/km(2), respectively, and 81 and 90% in areas baited during 2007 at 75 and 400 baits/km(2), respectively. Because tetracycline marking was poor in skunks, an estimate of vaccine efficacy was not possible. Aerial distribution of ONRAB vaccine baits seems to be a feasible tactic for controlling rabies in skunks and raccoons.

摘要

2006年8月至2007年期间,含有口服狂犬病疫苗(活腺病毒载体,即ONRAB)的诱饵被空投到加拿大安大略省西南部。2006年,在每平方公里投放150个诱饵的区域,浣熊(北美浣熊)对诱饵的接受率为62%和74%;在每平方公里投放300个诱饵的区域,接受率为75%和77%。2007年,在每平方公里分别投放75个和400个诱饵的区域,浣熊对诱饵的接受率分别在59%至80%和83%至87%之间。臭鼬对诱饵的接受率在不同区域有所不同(5% - 24%)。2006年,在每平方公里分别投放150个和300个诱饵的区域,浣熊的狂犬病病毒特异性血清转化率平均分别为66%和81%。2007年,在每平方公里分别投放75个和400个诱饵的区域,浣熊的血清转化率分别为76%和84%。臭鼬的血清转化率在不同区域有所不同(17% - 51%)。根据食用诱饵并发生血清转化的动物百分比判断,2006年在每平方公里分别投放150个和300个诱饵区域的浣熊疫苗效力平均分别为79%和87%,2007年在每平方公里分别投放75个和400个诱饵区域的疫苗效力分别为81%和90%。由于四环素标记在臭鼬身上效果不佳,无法估计疫苗效力。空投ONRAB疫苗诱饵似乎是控制臭鼬和浣熊狂犬病的一种可行策略。

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