Zhong Kaining, Chen Xinting, Zhang Junhao, Jiang Xiaoyu, Zhang Junhui, Huang Minyi, Bi Shuilian, Ju Chunmei, Luo Yongwen
College of Veterinary Medicine, South China Agricultural University, Guangzhou 510640, China.
School of Food Science, Guangdong Pharmaceutical University, Zhongshan 528458, China.
Vet Sci. 2024 Aug 5;11(8):353. doi: 10.3390/vetsci11080353.
Compared to traditional injected vaccines, oral vaccines offer significant advantages for the immunization of livestock and wildlife due to their ease of use, high compliance, improved safety, and potential to stimulate mucosal immune responses and induce systemic immunity against pathogens. This review provides an overview of the delivery methods for oral vaccines, and the factors that influence their immunogenicity. We also highlight the global progress and achievements in the development and use of oral vaccines for animals, shedding light on potential future applications in this field.
与传统注射疫苗相比，口服疫苗因其使用方便、依从性高、安全性好，以及具有刺激黏膜免疫反应和诱导针对病原体的全身免疫的潜力，在牲畜和野生动物免疫方面具有显著优势。本综述概述了口服疫苗的递送方法以及影响其免疫原性的因素。我们还重点介绍了动物口服疫苗研发和使用方面的全球进展与成就，为该领域未来的潜在应用提供参考。
