Rocha de Souza Micheline Cristiane, Marques Cybelle Teixeira, Guerra Dore Celina Maria, Ferreira da Silva Fernando Roberto, Oliveira Rocha Hugo Alexandre, Leite Edda Lisboa
J Appl Phycol. 2007 Apr;19(2):153-160. doi: 10.1007/s10811-006-9121-z. Epub 2006 Nov 30.
The in vitro antioxidant activities of the following six sulfated polysaccharides were investigated: iota, kappa and lambda carrageenans, which are widely used in the food industry, fucoidan (homofucan) from the edible seaweed Fucus vesiculosus and fucans (heterofucans) F0.5 and F1.1 from the seaweed Padina gymnospora. With respect to the inhibition of superoxide radical formation, fucoidan had an IC(50) (the half maximal inhibitory concentration) of 0.058 mg.mL(-1), while the IC(50) for the kappa, iota and lambda carrageenans were 0.112, 0.332 and 0.046 mg.mL(-1), respectively. All of the samples had an inhibitory effect on the formation of hydroxyl radicals. The results of peroxidation tests showed that fucoidan had an IC(50) of 1.250 mg.mL(-1) and that the kappa, iota and lambda carrageenans had an IC(50) of 2.753 and 2.338 and 0.323 mg.mL(-1), respectively. Fucan fractions showed low antioxidant activity relative to fucoidan. These results clearly indicate the beneficial effect of algal polysaccharides as antioxidants.
广泛应用于食品工业的iota、kappa和lambda角叉菜胶，可食用海藻墨角藻中的岩藻聚糖（同型岩藻聚糖）以及海藻裸叶藻中的岩藻聚糖（异型岩藻聚糖）F0.5和F1.1。关于超氧阴离子自由基形成的抑制作用，岩藻聚糖的IC50（半数最大抑制浓度）为0.058 mg·mL-1，而kappa、iota和lambda角叉菜胶的IC50分别为0.112、0.332和0.046 mg·mL-1。所有样品对羟自由基的形成均有抑制作用。过氧化试验结果表明，岩藻聚糖的IC50为1.250 mg·mL-1，kappa、iota和lambda角叉菜胶的IC50分别为2.753、2.338和0.323 mg·mL-1。相对于岩藻聚糖，岩藻聚糖级分显示出较低的抗氧化活性。这些结果清楚地表明了藻类多糖作为抗氧化剂的有益作用。
