Meinke Martina, Abdollahnia Mandana, Gähr Frank, Platzek Thomas, Sterry Wolfram, Lademann Jürgen
Center of Experimental and Applied Cutaneous Physiology, Department of Dermatology and Allergology, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Exp Dermatol. 2009 Sep;18(9):789-92. doi: 10.1111/j.1600-0625.2009.00885.x. Epub 2009 Apr 22.
The amount of textile dye migration from the textile and penetration into the skin is relevant when assessing the risk of textile dyes. In this paper, in vivo methods were developed using a harmless textile dye with a strong fluorescence and were then compared with in vitro methods. For the in vivo method, the textile was applied to the lower back of six volunteers wearing the textile 12 h and to the lower back of 12 volunteers during 30 min active sport. The maximum skin absorption of 55 +/- 17 ng/cm(2) was obtained in the group engaged in sports. The in vitro methods, which involved the application of the textile to the pig ear skin, was shown to yield similar results to the 12 h in vivo group (31.2 +/- 9.6 ng/cm(2) vs 27 +/- 14 ng/cm(2)). The migration of the textiles into artificial sweat resulted in approximately 20 microg/cm(2). The disadvantage of such textile extract applications on pig ear skin is discussed. It could be demonstrated that the absorption of the dye is strongly correlated to the amount of sweat, whereas the contact time was less important.
在评估纺织染料的风险时，纺织染料从纺织品迁移并渗透到皮肤中的量是相关的。在本文中，使用具有强荧光的无害纺织染料开发了体内方法，然后将其与体外方法进行比较。对于体内方法，将纺织品应用于六名穿着该纺织品12小时的志愿者的下背部，并应用于12名志愿者在30分钟剧烈运动期间的下背部。在进行运动的组中获得了最大皮肤吸收量为55±17 ng/cm²。体外方法涉及将纺织品应用于猪耳皮肤，结果显示与12小时体内组的结果相似（31.2±9.6 ng/cm²对27±14 ng/cm²）。纺织品向人工汗液中的迁移量约为20μg/cm²。讨论了这种在猪耳皮肤上应用纺织提取物的缺点。可以证明，染料的吸收与汗液量密切相关，而接触时间则不太重要。
