• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Preliminary evidence for progressive prefrontal abnormalities in adolescents and young adults with bipolar disorder.双相情感障碍青少年和青年成人前额叶进行性异常的初步证据。
J Int Neuropsychol Soc. 2009 May;15(3):476-81. doi: 10.1017/S1355617709090584.
2
Age, rapid-cycling, and pharmacotherapy effects on ventral prefrontal cortex in bipolar disorder: a cross-sectional study.年龄、快速循环及药物治疗对双相情感障碍患者腹侧前额叶皮层的影响：一项横断面研究
Biol Psychiatry. 2006 Apr 1;59(7):611-8. doi: 10.1016/j.biopsych.2005.08.031. Epub 2006 Jan 18.
3
Anterior Cortical Development During Adolescence in Bipolar Disorder.双相情感障碍青少年期的前额叶皮质发育
Biol Psychiatry. 2016 Feb 15;79(4):303-10. doi: 10.1016/j.biopsych.2015.03.026. Epub 2015 Apr 6.
4
Longitudinal Diffusion Tensor Imaging Study of Adolescents and Young Adults With Bipolar Disorder.青少年和年轻成人双相障碍的纵向扩散张量成像研究。
J Am Acad Child Adolesc Psychiatry. 2018 Feb;57(2):111-117. doi: 10.1016/j.jaac.2017.11.014. Epub 2017 Nov 26.
5
Preliminary evidence for persistent abnormalities in amygdala volumes in adolescents and young adults with bipolar disorder.双相情感障碍青少年和青年杏仁核体积持续异常的初步证据。
Bipolar Disord. 2005 Dec;7(6):570-6. doi: 10.1111/j.1399-5618.2005.00264.x.
6
Gray and white matter differences in adolescents and young adults with prior suicide attempts across bipolar and major depressive disorders.双相障碍和重度抑郁症患者中既往有自杀未遂史的青少年和年轻成人的灰质和白质差异。
J Affect Disord. 2019 Feb 15;245:1089-1097. doi: 10.1016/j.jad.2018.11.095. Epub 2018 Nov 22.
7
Functional connectivity between ventral prefrontal cortex and amygdala at low frequency in the resting state in bipolar disorder.双相障碍患者静息状态下腹侧前额叶皮质和杏仁核低频功能连接。
Psychiatry Res. 2010 Jun 30;182(3):207-10. doi: 10.1016/j.pscychresns.2010.04.002. Epub 2010 May 20.
8
Towards a neurodevelopmental model of bipolar disorder: a critical review of trait- and state-related functional neuroimaging in adolescents and young adults.迈向双相情感障碍的神经发育模型：对青少年和青年中与特质及状态相关的功能神经影像学的批判性综述。
Mol Psychiatry. 2025 Mar;30(3):1089-1101. doi: 10.1038/s41380-024-02758-4. Epub 2024 Sep 27.
9
Age associations with neural processing of reward anticipation in adolescents with bipolar disorders.双相情感障碍青少年中与奖励预期神经加工的年龄关联。
Neuroimage Clin. 2016 Mar 18;11:476-485. doi: 10.1016/j.nicl.2016.03.013. eCollection 2016.
10
Corticolimbic functional connectivity in adolescents with bipolar disorder.双相障碍青少年的皮质边缘功能连接。
PLoS One. 2012;7(11):e50177. doi: 10.1371/journal.pone.0050177. Epub 2012 Nov 21.

引用本文的文献

1
Mapping Structural Neuroimaging Trajectories in Bipolar Disorder: Neurobiological and Clinical Implications.双相情感障碍的结构神经影像学轨迹映射：神经生物学及临床意义
Biol Psychiatry. 2025 Aug 15;98(4):311-321. doi: 10.1016/j.biopsych.2025.02.009. Epub 2025 Feb 14.
2
Towards a neurodevelopmental model of bipolar disorder: a critical review of trait- and state-related functional neuroimaging in adolescents and young adults.迈向双相情感障碍的神经发育模型：对青少年和青年中与特质及状态相关的功能神经影像学的批判性综述。
Mol Psychiatry. 2025 Mar;30(3):1089-1101. doi: 10.1038/s41380-024-02758-4. Epub 2024 Sep 27.
3
Differences in Quantification of the Metabotropic Glutamate Receptor 5 Across Bipolar Disorder and Major Depressive Disorder.双相障碍和重度抑郁症中代谢型谷氨酸受体 5 定量的差异。
Biol Psychiatry. 2023 Jun 15;93(12):1099-1107. doi: 10.1016/j.biopsych.2022.10.018. Epub 2022 Nov 8.
4
Neuroimaging Studies of Brain Structure in Older Adults with Bipolar Disorder: A Review.双相情感障碍老年患者脑结构的神经影像学研究：综述
J Psychiatr Brain Sci. 2022;7(4). doi: 10.20900/jpbs.20220006. Epub 2022 Aug 25.
5
Neural functional connectivity changes to psychosocial stress in young adults with bipolar disorder and preliminary associations with clinical trajectories.双相障碍青年对心理社会压力的神经功能连接变化及与临床轨迹的初步关联。
Bipolar Disord. 2022 May;24(3):298-309. doi: 10.1111/bdi.13127. Epub 2021 Sep 24.
6
Automatic Diagnosis of Bipolar Disorder Using Optical Coherence Tomography Data and Artificial Intelligence.利用光学相干断层扫描数据和人工智能自动诊断双相情感障碍
J Pers Med. 2021 Aug 18;11(8):803. doi: 10.3390/jpm11080803.
7
Anomalous brain gyrification patterns in major psychiatric disorders: a systematic review and transdiagnostic integration.主要精神疾病中的异常脑回模式：系统综述和跨诊断整合。
Transl Psychiatry. 2021 Mar 17;11(1):176. doi: 10.1038/s41398-021-01297-8.
8
Neuroprogression as an Illness Trajectory in Bipolar Disorder: A Selective Review of the Current Literature.双相情感障碍中作为疾病轨迹的神经进展：当前文献的选择性综述
Brain Sci. 2021 Feb 23;11(2):276. doi: 10.3390/brainsci11020276.
9
Childhood maltreatment, prefrontal-paralimbic gray matter volume, and substance use in young adults and interactions with risk for bipolar disorder.儿童期虐待、前额叶-边缘灰质体积与年轻人的物质使用及与双相障碍风险的相互作用
Sci Rep. 2021 Jan 8;11(1):123. doi: 10.1038/s41598-020-80407-w.
10
Structural and Functional Brain Correlates of Neuroprogression in Bipolar Disorder.双相障碍神经进展的结构和功能脑关联。
Curr Top Behav Neurosci. 2021;48:197-213. doi: 10.1007/7854_2020_177.

本文引用的文献

1
Integrated Intensity and Point-Feature Nonrigid Registration.综合强度与点特征非刚性配准
Med Image Comput Comput Assist Interv. 2001 Sep 2;3216(2004):763-770. doi: 10.1901/jaba.2001.3216-763.
2
Brain Shape Characterization from Deformation.基于变形的脑形状特征描述
Proc IEEE Int Symp Biomed Imaging. 2006;3(1625124):1140-1143.
3
Dynamic mapping of cortical development before and after the onset of pediatric bipolar illness.小儿双相情感障碍发病前后皮质发育的动态图谱
J Child Psychol Psychiatry. 2007 Sep;48(9):852-62. doi: 10.1111/j.1469-7610.2007.01747.x.
4
Neural circuitry engaged during unsuccessful motor inhibition in pediatric bipolar disorder.小儿双相情感障碍患者运动抑制失败时所涉及的神经回路。
Am J Psychiatry. 2007 Jan;164(1):52-60. doi: 10.1176/ajp.2007.164.1.A52.
5
Affective neural circuitry during facial emotion processing in pediatric bipolar disorder.儿童双相情感障碍患者面部情绪加工过程中的情感神经回路
Biol Psychiatry. 2007 Jul 15;62(2):158-67. doi: 10.1016/j.biopsych.2006.07.011. Epub 2006 Nov 9.
6
Voxel-based study of structural changes in first-episode patients with bipolar disorder.基于体素的双相情感障碍首发患者结构变化研究。
Biol Psychiatry. 2007 Mar 15;61(6):776-81. doi: 10.1016/j.biopsych.2006.05.042. Epub 2006 Oct 6.
7
Limbic hyperactivation during processing of neutral facial expressions in children with bipolar disorder.双相情感障碍患儿在处理中性面部表情时边缘系统过度激活。
Proc Natl Acad Sci U S A. 2006 Jun 6;103(23):8900-5. doi: 10.1073/pnas.0603246103. Epub 2006 May 30.
8
Age, rapid-cycling, and pharmacotherapy effects on ventral prefrontal cortex in bipolar disorder: a cross-sectional study.年龄、快速循环及药物治疗对双相情感障碍患者腹侧前额叶皮层的影响：一项横断面研究
Biol Psychiatry. 2006 Apr 1;59(7):611-8. doi: 10.1016/j.biopsych.2005.08.031. Epub 2006 Jan 18.
9
Stroop performance in bipolar disorder: further evidence for abnormalities in the ventral prefrontal cortex.双相情感障碍中的斯特鲁普效应表现：腹侧前额叶皮质异常的进一步证据。
Bipolar Disord. 2006 Feb;8(1):28-39. doi: 10.1111/j.1399-5618.2006.00282.x.
10
Preliminary evidence for persistent abnormalities in amygdala volumes in adolescents and young adults with bipolar disorder.双相情感障碍青少年和青年杏仁核体积持续异常的初步证据。
Bipolar Disord. 2005 Dec;7(6):570-6. doi: 10.1111/j.1399-5618.2005.00264.x.

双相情感障碍青少年和青年成人前额叶进行性异常的初步证据。

Preliminary evidence for progressive prefrontal abnormalities in adolescents and young adults with bipolar disorder.

作者信息

Kalmar Jessica H, Wang Fei, Spencer Linda, Edmiston Erin, Lacadie Cheryl M, Martin Andrés, Constable R Todd, Duncan James S, Staib Lawrence H, Papademetris Xenophon, Blumberg Hilary P

机构信息

Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut 06511, USA.

出版信息

J Int Neuropsychol Soc. 2009 May;15(3):476-81. doi: 10.1017/S1355617709090584.

DOI:10.1017/S1355617709090584
PMID:19402934
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2852397/
Abstract

Previous cross-sectional study of ventral prefrontal cortex (VPFC) implicated progressive volume abnormalities during adolescence in bipolar disorder (BD). In the present study, a within-subject, longitudinal design was implemented to examine brain volume changes during adolescence/young adulthood. We hypothesized that VPFC volume decreases over time would be greater in adolescents/young adults with BD than in healthy comparison adolescents/young adults. Eighteen adolescents/young adults (10 with BD I and 8 healthy comparison participants) underwent two high-resolution magnetic resonance imaging scans over approximately 2 years. Regional volume changes over time were measured. Adolescents/young adults with BD displayed significantly greater volume loss over time, compared to healthy comparison participants, in a region encompassing VPFC and rostral PFC and extending to rostral anterior cingulate cortex (p < .05). Additional areas where volume change differed between groups were observed. While data should be interpreted cautiously due to modest sample size, this study provides preliminary evidence to support the presence of accelerated loss in VPFC and rostral PFC volume in adolescents/young adults with BD.

摘要

先前对腹侧前额叶皮层（VPFC）的横断面研究表明，双相情感障碍（BD）患者在青春期存在渐进性的体积异常。在本研究中，采用了受试者内纵向设计来检查青春期/青年期的脑容量变化。我们假设，与健康对照青少年/青年相比，BD青少年/青年的VPFC体积随时间的减少会更大。18名青少年/青年（10名BD-I患者和8名健康对照参与者）在大约2年的时间里接受了两次高分辨率磁共振成像扫描。测量了随时间的区域体积变化。与健康对照参与者相比，BD青少年/青年在包括VPFC和喙状前额叶皮层并延伸至喙状前扣带回皮层的区域中，随时间显示出明显更大的体积损失（p <.05）。还观察到两组之间体积变化不同的其他区域。由于样本量较小，数据应谨慎解释，但本研究提供了初步证据，支持BD青少年/青年中VPFC和喙状前额叶皮层体积加速损失的存在。