Zhao De-qiang, Pan Su-yue, Chen Jian-hui, Yang Wen-jun
Department of Neurology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Nan Fang Yi Ke Da Xue Xue Bao. 2009 Apr;29(4):807-8.
To study the relationship between cystatin C and cerebral infarction and explore the role of cystatin C in the protection against cerebral infarction.
Eighty-three patients with cerebral infarction and 71 randomly selected age- and gender-matched patients in the Department of Neurology (control group) were enrolled in this study. Fasting whole blood (3 ml) was obtained from the patients in both groups and the sera were separated to determine the levels of cystatin C using particle reinforced immunoturbidimetric assay.
The serum cystatin C level was significantly lower in the cerebral infarction group than in the control group (1.62-/+0.31 vs 2.23-/+0.22 mg/L, P<0.01).
Cystatin C is closely related to cerebral infarction probably as a protective factor against cerebral infarction.
研究胱抑素C与脑梗死的关系，探讨胱抑素C在预防脑梗死中的作用。
本研究纳入83例脑梗死患者及神经内科随机选取的71例年龄、性别匹配的患者（对照组）。采集两组患者空腹全血（3 ml），分离血清，采用颗粒增强免疫比浊法测定胱抑素C水平。
脑梗死组血清胱抑素C水平显著低于对照组（1.62±0.31 vs 2.23±0.22 mg/L，P<0.01）。
胱抑素C与脑梗死密切相关，可能是预防脑梗死的保护因素。
