Tavakkoli Hamid, Haghdani Saeid, Emami Mohammad Hassan, Adilipour Haideh, Tavakkoli Mahbobeh, Tavakkoli Monireh
Department of Gastroenterology, Al-Zahra Hospital, Isfahan, Iran.
Indian J Gastroenterol. 2008 Nov-Dec;27(6):239-41.
Ramadan fasting may induce changes in gastrointestinal physiology. The effect of this fasting on inflammatory bowel disease (IBD) is not known. We conducted a cohort study in the month of Ramadan in 2006 to assess the effect of Ramadan fasting on IBD. Sixty patients with IBD, who were in remission and undertook fasting according to their own free will underwent assessment of quality-of-life (QoL) parameters, psychological state and the severity of symptoms before and after Ramadan. There was no correlation between the number of fasting days and the severity of the disease, QoL and psychological state of the patients. QoL did not change after Ramadan. Younger patients with ulcerative colitis (UC) fasted for a greater number of days (p=0.01) compared to older patients. The mean score of anxiety, using a modified version of the Hospital Anxiety and Depression Scale was 12.7 (6.0) before Ramadan in women with UC, and decreased to 9.8 (4.4) afterfasting (p=0.026). Men with UC had a mean score of colitis activity index of 3.5 before Ramadan, which decreased to 1.7 after fasting (p=0.008). It appears that Ramadan fasting does not impose serious risks on patients with IBD.
斋月禁食可能会引起胃肠道生理变化。这种禁食对炎症性肠病（IBD）的影响尚不清楚。我们在2006年斋月期间进行了一项队列研究，以评估斋月禁食对IBD的影响。60例处于缓解期且自愿禁食的IBD患者在斋月前后接受了生活质量（QoL）参数、心理状态和症状严重程度的评估。禁食天数与疾病严重程度、患者的QoL和心理状态之间没有相关性。斋月后QoL没有变化。与老年患者相比，年轻的溃疡性结肠炎（UC）患者禁食天数更多（p=0.01）。使用改良版医院焦虑抑郁量表，UC女性患者在斋月前焦虑平均评分为12.7（6.0），禁食后降至9.8（4.4）（p=0.026）。UC男性患者在斋月前结肠炎活动指数平均评分为3.5，禁食后降至1.7（p=0.008）。看来斋月禁食不会给IBD患者带来严重风险。
