Belichenko V M, Shoshenko K A
Ontogenez. 2009 Mar-Apr;40(2):126-35.
A restructuring of the capillary bed-from the embryonic structure with a three-dimensional network of wide and long protocapillaries to the mature structure with high density of thin and short capillaries along the fibers-has been demonstrated in the chick skeletal muscle on embryonic days 10-19 by morphometric analysis. In this case, the volumetric flow rate and capillary luminal area per cm3 of the muscle remained unaltered, while the blood volume in it significantly dropped. The response of muscle circulation to nitroprusside (increase) and noradrenaline (decrease) appeared in 19-day-old embryos, but this response could develop only under conditions of initially low or high bloodstream, respectively. We propose that the arterial trunk lumen area to the total capillary lumen area remains constant as the intraorganic circulation is formed, which provides for the required linear blood velocity in capillaries.
通过形态计量分析已证实在胚胎第10至19天的鸡骨骼肌中，毛细血管床发生了重构——从具有宽而长的原始毛细血管三维网络的胚胎结构转变为沿纤维具有高密度细而短的毛细血管的成熟结构。在这种情况下，每立方厘米肌肉的体积流速和毛细血管腔面积保持不变，而其中的血容量显著下降。肌肉循环对硝普钠（增加）和去甲肾上腺素（减少）的反应在19日龄胚胎中出现，但这种反应分别仅在最初血流低或高的条件下才会发生。我们认为，随着器官内循环的形成，动脉干腔面积与总毛细血管腔面积之比保持恒定，这为毛细血管中所需的线性血流速度提供了保障。
