Long Cheng-Yu, Hsu Chun-Shuo, Wu Ming-Ping, Liu Cheng-Min, Chiang Po-Hui, Juan Yung-Shun, Tsai Eing-Mei
Graduate Institute of Medicine, Center of Excellence for Environmental Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
Int Urogynecol J. 2011 May;22(5):535-42. doi: 10.1007/s00192-010-1312-0. Epub 2010 Nov 16.
The aim of this study was to identify the predictors of improved overactive bladder (OAB) symptoms after transvaginal mesh repair.
Eighty women with pelvic organ prolapse (POP) stage II to IV reporting OAB symptoms were scheduled for transvaginal mesh procedures. Preoperative and postoperative assessments included a bladder diary, urodynamics, and a personal interview about urinary symptoms.
Sixty-three (78.8%) women experienced improvement of OAB symptoms (Improvement group), and 17 (21.2%) women remained unchanged or worsened (Persistence group) postoperatively. A univariate analysis of patients' characteristics showed no difference between two groups regarding parity, diabetes, hypertension, prolapse status, preoperative urodynamic parameters, and urinary symptoms (P > 0.05). However, the age (P = 0.042) and preoperative detrusor overactivity (DO) (P = 0.03) were two significant predictors of postoperative OAB improvement.
Women with POP may experience improvement of their OAB symptoms after transvaginal mesh repair. Both age and DO were two predictors in our univariate analysis, and the latter was the only significant predictor of symptom relief after adjusting age factor.
本研究旨在确定经阴道网片修补术后膀胱过度活动症（OAB）症状改善的预测因素。
80例报告有OAB症状的盆腔器官脱垂（POP）II至IV期女性计划接受经阴道网片手术。术前和术后评估包括膀胱日记、尿动力学检查以及关于泌尿症状的个人访谈。
63例（78.8%）女性术后OAB症状改善（改善组），17例（21.2%）女性术后症状无变化或加重（持续组）。对患者特征进行单因素分析显示，两组在产次、糖尿病、高血压、脱垂状态、术前尿动力学参数及泌尿症状方面无差异（P>0.05）。然而，年龄（P = 0.042）和术前逼尿肌过度活动（DO）（P = 0.03）是术后OAB改善的两个重要预测因素。
POP女性经阴道网片修补术后OAB症状可能会改善。在我们的单因素分析中，年龄和DO均为预测因素，调整年龄因素后，DO是症状缓解的唯一显著预测因素。
