Lawndy Sameh S S, Kluivers Kirsten B, Milani Alfredo L, Withagen Mariella I J, Hendriks Jan C M, Vierhout Mark E
791 Department of Obstetrics and Gynaecology, Radboud University Nijmegen Medical Centre, PO Box 9101, 6500 HB Nijmegen, The Netherlands.
Int Urogynecol J. 2011 May;22(5):543-9. doi: 10.1007/s00192-010-1321-z. Epub 2010 Nov 23.
The factors influencing a patient's subjective improvement 1 year after pelvic organ prolapse (POP) surgery were studied.
Women after POP surgery were divided into improved and non-improved group based on their score on the questionnaire Patient Global Impression of Improvement (PGI-I) 1 year after surgery. Anatomical and functional outcomes were assessed as influencing factors for improvement using multivariate logistic regression.
Three hundred eighty-six (386) women were included in the study, of whom 40 (10%) had not subjectively improved. First POP operation, symptoms and bother of genital prolapse and overactive bladder, and anterior compartment anatomy were independent factors related to subjective improvement. A threshold needed to be reached in these parameters.
The first operation was more often associated with subjective improvement, and both anatomical and functional outcomes were of importance. The mere finding of a statistical significant improvement was no guarantee for subjective improvement after POP surgery.
本研究旨在探讨影响盆腔器官脱垂（POP）手术后1年患者主观改善情况的因素。
根据患者术后1年的“患者整体改善印象”（PGI-I）问卷评分，将接受POP手术的女性分为改善组和未改善组。采用多因素逻辑回归分析评估解剖学和功能结局作为改善的影响因素。
本研究共纳入386名女性，其中40名（10%）主观上未得到改善。首次POP手术、生殖器脱垂和膀胱过度活动症的症状及困扰，以及前盆腔解剖结构是与主观改善相关的独立因素。这些参数需要达到一个阈值。
首次手术更常与主观改善相关，解剖学和功能结局均很重要。仅仅发现有统计学上的显著改善并不能保证POP手术后患者主观上会得到改善。
