Ju Woong, Myung Seung-Kwon, Kim Yeol, Choi Hyuck Jae, Kim Seung Cheol
Department of Obstetrics and Gynecology, Medical Research Institute, Ewha Womans University, Seoul, Korea.
Int J Gynecol Cancer. 2009 Apr;19(3):400-6. doi: 10.1111/IGC.0b013e3181a1caf8.
This meta-analysis was performed to investigate the outcome of laparoscopic surgery for endometrial carcinoma compared with laparotomy.
We searched the MEDLINE (PubMed), EMBASE, and Cochrane Review databases in September 2007. Three independent evaluators selected the articles according to predetermined selection criteria.
Thirteen comparative studies (5 prospective and 8 retrospective) that met the selection criteria were included. In a fixed-effects meta-analysis, the overall survival and therecurrence rate showed no significant differences between the laparoscopy and the laparotomy groups, with odds ratios of 0.84 (95% confidence interval, 0.64-1.62) and 0.90 (95% confidence interval, 0.49-1.16), respectively. However, the complication rate was lower in the laparoscopy group than in the laparotomy group with an odds ratio of 0.43 (95% confidence interval, 0.32-0.58).
The survival outcome and recurrence rate after laparoscopic surgery for endometrial carcinoma were similar to those in the laparotomy procedures. However, the complication rate was lower after laparoscopy compared with laparotomy.
本荟萃分析旨在研究子宫内膜癌腹腔镜手术与开腹手术相比的结果。
我们于2007年9月检索了MEDLINE（PubMed）、EMBASE和Cochrane系统评价数据库。三位独立评估者根据预先确定的选择标准筛选文章。
纳入了13项符合选择标准的比较研究（5项前瞻性研究和8项回顾性研究）。在固定效应荟萃分析中，腹腔镜手术组和开腹手术组的总生存率和复发率无显著差异，优势比分别为0.84（95%置信区间，0.64 - 1.62）和0.90（95%置信区间，0.49 - 1.16）。然而，腹腔镜手术组的并发症发生率低于开腹手术组，优势比为0.43（95%置信区间，0.32 - 0.58）。
子宫内膜癌腹腔镜手术后的生存结果和复发率与开腹手术相似。然而，与开腹手术相比，腹腔镜手术后的并发症发生率较低。
