Mohler-Kuo Meichun, Zellweger Ueli, Duran Aysun, Hohl Michael K, Gutzwiller Felix, Mutsch Margot
Institute of Social and Preventive Medicine, University of Zurich, Hirschengraben 84, 8001 Zurich, Switzerland.
Hum Reprod. 2009 Aug;24(8):1930-8. doi: 10.1093/humrep/dep103. Epub 2009 May 4.
The purpose of this study was to investigate attitudes towards the donation of surplus embryos among couples with cryopreserved embryos/zygotes, and to identify correlates associated with attitudes toward the destinations of surplus embryos/zygotes.
Eleven of 19 Swiss in vitro fertilization (IVF) centers in existence in 2004 participated in the survey. Questionnaires were sent to 888 eligible couples; 458 men (52%) and 468 women (53%) returned them.
Fifty-two percent of the participants supported the donation of surplus embryos to other couples, but divided opinions on the disclosure of biological parents' identities were identified. About 70% of participants indicated that donations of surplus embryos for medical research or therapy should be allowed, following strict regulations. Multiple logistic regression analyses revealed couples' position on the moral status of an embryo as the strongest predictor of attitudes toward all destinations of surplus embryos. Having children due to IVF/Intra-Cytoplasmic Sperm Injection (ICSI) treatment was negatively associated with attitudes towards donations to other couples. Perceived importance of religion, age >40, being a resident of the French-speaking region and unsuccessful IVF/ICSI treatment experiences were predictive of supporting donations for medical research.
Swiss couples with cryopreserved embryos/zygotes are open to different options related to donating, rather than discarding, surplus embryos.
本研究旨在调查拥有冷冻胚胎/受精卵的夫妇对捐赠多余胚胎的态度，并确定与对多余胚胎/受精卵去向的态度相关的因素。
2004年瑞士现存的19个体外受精（IVF）中心中有11个参与了此次调查。向888对符合条件的夫妇发放了问卷；458名男性（52%）和468名女性（53%）回复了问卷。
52%的参与者支持将多余胚胎捐赠给其他夫妇，但对于是否披露生物学父母的身份存在不同意见。约70%的参与者表示，在严格规定下，应允许将多余胚胎用于医学研究或治疗。多项逻辑回归分析显示，夫妇对胚胎道德地位的立场是对多余胚胎所有去向态度的最强预测因素。因体外受精/卵胞浆内单精子注射（ICSI）治疗而育有子女与对捐赠给其他夫妇的态度呈负相关。宗教信仰的重要性、年龄>40岁、居住在法语区以及体外受精/ICSI治疗失败的经历是支持医学研究捐赠的预测因素。
拥有冷冻胚胎/受精卵的瑞士夫妇对与捐赠而非丢弃多余胚胎相关的不同选择持开放态度。
