• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

利用多余胚胎治疗帕金森病在瑞典人群中的看法:一项定性研究。

Perceptions on using surplus embryos for the treatment of Parkinson's disease among the Swedish population: a qualitative study.

机构信息

Centre for Research Ethics and Bioethics, Uppsala University, Box 564, 751 22, Uppsala, Sweden.

出版信息

BMC Med Ethics. 2022 Mar 4;23(1):15. doi: 10.1186/s12910-022-00759-y.

DOI:10.1186/s12910-022-00759-y
PMID:35246133
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8895863/
Abstract

BACKGROUND

Human embryonic stem cells are currently used for developing treatment against Parkinson's disease (PD). However, the use of ES cells is surrounded with moral concerns. Research regarding the public's attitudes can form an important basis for policymaking. The aim was to explore the perceptions of the public on using donated human embryos for developing treatment of Parkinson's Disease.

METHODS

Semi-structured individual qualitative interviews were conducted with 11 members of the general population in Sweden. Interviews were analyzed with thematic content analyses.

RESULTS

Four categories and additional sub-categories; Different views on the embryo requires delicacy, Using embryos to treat Parkinson's disease, Doing things in the right way, and Communication, media, and public opinion. In general, respondents were positive towards the usage of embryotic stem cells to treat PD, but the usage were conditioned and specific terms were demanded. Informed consent from both donors were required and delicacy and sensitivity when working with embryos were needed.

CONCLUSIONS

It was perceived better to use surplus embryos to treat PD increase is than to discard them, also among those who perceived the embryo as "a potential life." The participants raised several conditions under usage for treatment should be allowed. Even if the embryos otherwise are going to be discarded, usage requires informed consent from the donating couples.

摘要

背景

人类胚胎干细胞目前被用于开发治疗帕金森病(PD)的方法。然而,胚胎干细胞的使用存在道德问题。对公众态度的研究可以为决策制定提供重要依据。本研究旨在探讨公众对使用捐赠的人类胚胎开发帕金森病治疗方法的看法。

方法

在瑞典,对 11 名普通民众进行了半结构化的个人定性访谈。采用主题内容分析法对访谈进行分析。

结果

得出了四个类别和附加的子类别;对胚胎的不同看法需要谨慎、使用胚胎治疗帕金森病、以正确的方式做事、以及沟通、媒体和公众意见。总的来说,受访者对使用胚胎干细胞治疗 PD 持积极态度,但使用条件和具体要求受到限制。需要来自供体的知情同意,并且在处理胚胎时需要谨慎和敏感。

结论

使用多余的胚胎来治疗 PD 增加是比丢弃它们更好的选择,即使那些认为胚胎是“潜在生命”的人也是如此。参与者提出了一些允许在特定条件下进行治疗的使用胚胎的条件。即使胚胎最终将被丢弃,使用也需要捐赠夫妇的知情同意。

相似文献

1
Perceptions on using surplus embryos for the treatment of Parkinson's disease among the Swedish population: a qualitative study.利用多余胚胎治疗帕金森病在瑞典人群中的看法:一项定性研究。
BMC Med Ethics. 2022 Mar 4;23(1):15. doi: 10.1186/s12910-022-00759-y.
2
Would you consider donating your left-over embryos to treat Parkinson's disease? Interviews with individuals that underwent IVF in Sweden.你会考虑将剩余的胚胎捐赠出来用于治疗帕金森病吗?对在瑞典接受试管婴儿技术的个体进行的访谈。
BMC Med Ethics. 2022 Dec 3;23(1):124. doi: 10.1186/s12910-022-00864-y.
3
Attitudes and values among the Swedish general public to using human embryonic stem cells for medical treatment.瑞典公众对使用人类胚胎干细胞进行医疗的态度和价值观。
BMC Med Ethics. 2022 Dec 22;23(1):138. doi: 10.1186/s12910-022-00878-6.
4
Patients' views on using human embryonic stem cells to treat Parkinson's disease: an interview study.患者对使用人胚胎干细胞治疗帕金森病的看法:一项访谈研究。
BMC Med Ethics. 2022 Oct 19;23(1):102. doi: 10.1186/s12910-022-00840-6.
5
Attitudes of couples towards the destination of surplus embryos: results among couples with cryopreserved embryos in Switzerland.夫妻对剩余胚胎去向的态度:瑞士有冷冻胚胎的夫妻的调查结果
Hum Reprod. 2009 Aug;24(8):1930-8. doi: 10.1093/humrep/dep103. Epub 2009 May 4.
6
Donation of surplus frozen pre-embryos to research in Israel: underlying motivations.向以色列研究领域捐赠多余冷冻胚胎:潜在动机
Isr J Health Policy Res. 2016 Nov 5;5:25. doi: 10.1186/s13584-016-0085-4. eCollection 2016.
7
Attitudes towards embryo donation among infertile couples with frozen embryos.不孕夫妇对冷冻胚胎的捐赠态度。
Hum Reprod. 2013 Sep;28(9):2432-9. doi: 10.1093/humrep/det252. Epub 2013 Jun 11.
8
Survey of 243 ART patients having made a final disposition decision about their surplus cryopreserved embryos: the crucial role of symbolic embryo representation.对243名已对其剩余冷冻胚胎做出最终处置决定的辅助生殖技术患者的调查:象征性胚胎表征的关键作用
Hum Reprod. 2016 Jul;31(7):1508-14. doi: 10.1093/humrep/dew104. Epub 2016 May 10.
9
'Not taken in by media hype': how potential donors, recipients and members of the general public perceive stem cell research.“不为媒体炒作所动”:潜在捐赠者、受赠者及公众如何看待干细胞研究。
Hum Reprod. 2009 May;24(5):1106-13. doi: 10.1093/humrep/den496. Epub 2009 Jan 24.
10
Using Surplus Embryos and Research Embryos in Stem Cell Research: Ethical Viewpoints of Buddhist, Hindu and Catholic Leaders in Malaysia on the Permissibility of Research.利用剩余胚胎和研究胚胎进行干细胞研究:马来西亚佛教、印度教和天主教领袖对研究可行性的伦理观点。
Sci Eng Ethics. 2018 Feb;24(1):129-149. doi: 10.1007/s11948-017-9893-3. Epub 2017 Mar 9.

引用本文的文献

1
Attitudes and values among the Swedish general public to using human embryonic stem cells for medical treatment.瑞典公众对使用人类胚胎干细胞进行医疗的态度和价值观。
BMC Med Ethics. 2022 Dec 22;23(1):138. doi: 10.1186/s12910-022-00878-6.
2
Would you consider donating your left-over embryos to treat Parkinson's disease? Interviews with individuals that underwent IVF in Sweden.你会考虑将剩余的胚胎捐赠出来用于治疗帕金森病吗?对在瑞典接受试管婴儿技术的个体进行的访谈。
BMC Med Ethics. 2022 Dec 3;23(1):124. doi: 10.1186/s12910-022-00864-y.
3
Patients' views on using human embryonic stem cells to treat Parkinson's disease: an interview study.患者对使用人胚胎干细胞治疗帕金森病的看法:一项访谈研究。
BMC Med Ethics. 2022 Oct 19;23(1):102. doi: 10.1186/s12910-022-00840-6.

本文引用的文献

1
Donation of surplus frozen pre-embryos to research in Israel: underlying motivations.向以色列研究领域捐赠多余冷冻胚胎:潜在动机
Isr J Health Policy Res. 2016 Nov 5;5:25. doi: 10.1186/s13584-016-0085-4. eCollection 2016.
2
Concise Review: Human Embryonic Stem Cells-What Have We Done? What Are We Doing? Where Are We Going?简明综述:人类胚胎干细胞——我们做了什么?我们正在做什么?我们将何去何从?
Stem Cells. 2017 Jan;35(1):17-25. doi: 10.1002/stem.2450. Epub 2016 Jul 17.
3
Factors associated with the donation and non-donation of embryos for research: a systematic review.与胚胎捐赠和非捐赠用于研究相关的因素:系统评价。
Hum Reprod Update. 2014 Sep-Oct;20(5):641-55. doi: 10.1093/humupd/dmu026. Epub 2014 Jun 6.
4
Attitudes toward embryo donation among staff at in vitro fertilization clinics.体外受精诊所工作人员对胚胎捐赠的态度。
Acta Obstet Gynecol Scand. 2014 Aug;93(8):765-70. doi: 10.1111/aogs.12407. Epub 2014 May 24.
5
Attitudes towards embryo donation in Swedish women and men of reproductive age.瑞典育龄男女对胚胎捐赠的态度。
Ups J Med Sci. 2013 Aug;118(3):187-95. doi: 10.3109/03009734.2013.808294. Epub 2013 Jun 20.
6
Asian immigrants to the United States are less likely to donate cryopreserved embryos for research use.亚洲移民到美国不太可能捐赠冷冻胚胎用于研究。
Fertil Steril. 2011 Apr;95(5):1672-6. doi: 10.1016/j.fertnstert.2011.01.123. Epub 2011 Feb 17.
7
Attitudes of couples towards the destination of surplus embryos: results among couples with cryopreserved embryos in Switzerland.夫妻对剩余胚胎去向的态度:瑞士有冷冻胚胎的夫妻的调查结果
Hum Reprod. 2009 Aug;24(8):1930-8. doi: 10.1093/humrep/dep103. Epub 2009 May 4.
8
Analysing and presenting qualitative data.分析和呈现定性数据。
Br Dent J. 2008 Apr 26;204(8):429-32. doi: 10.1038/sj.bdj.2008.292.
9
Induction of pluripotent stem cells from adult human fibroblasts by defined factors.通过特定因子将成人成纤维细胞诱导为多能干细胞。
Cell. 2007 Nov 30;131(5):861-72. doi: 10.1016/j.cell.2007.11.019.
10
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors.通过特定因子从小鼠胚胎和成体成纤维细胞培养物中诱导多能干细胞。
Cell. 2006 Aug 25;126(4):663-76. doi: 10.1016/j.cell.2006.07.024. Epub 2006 Aug 10.