Suppr超能文献

利用多余胚胎治疗帕金森病在瑞典人群中的看法:一项定性研究。

Perceptions on using surplus embryos for the treatment of Parkinson's disease among the Swedish population: a qualitative study.

机构信息

Centre for Research Ethics and Bioethics, Uppsala University, Box 564, 751 22, Uppsala, Sweden.

出版信息

BMC Med Ethics. 2022 Mar 4;23(1):15. doi: 10.1186/s12910-022-00759-y.

Abstract

BACKGROUND

Human embryonic stem cells are currently used for developing treatment against Parkinson's disease (PD). However, the use of ES cells is surrounded with moral concerns. Research regarding the public's attitudes can form an important basis for policymaking. The aim was to explore the perceptions of the public on using donated human embryos for developing treatment of Parkinson's Disease.

METHODS

Semi-structured individual qualitative interviews were conducted with 11 members of the general population in Sweden. Interviews were analyzed with thematic content analyses.

RESULTS

Four categories and additional sub-categories; Different views on the embryo requires delicacy, Using embryos to treat Parkinson's disease, Doing things in the right way, and Communication, media, and public opinion. In general, respondents were positive towards the usage of embryotic stem cells to treat PD, but the usage were conditioned and specific terms were demanded. Informed consent from both donors were required and delicacy and sensitivity when working with embryos were needed.

CONCLUSIONS

It was perceived better to use surplus embryos to treat PD increase is than to discard them, also among those who perceived the embryo as "a potential life." The participants raised several conditions under usage for treatment should be allowed. Even if the embryos otherwise are going to be discarded, usage requires informed consent from the donating couples.

摘要

背景

人类胚胎干细胞目前被用于开发治疗帕金森病(PD)的方法。然而,胚胎干细胞的使用存在道德问题。对公众态度的研究可以为决策制定提供重要依据。本研究旨在探讨公众对使用捐赠的人类胚胎开发帕金森病治疗方法的看法。

方法

在瑞典,对 11 名普通民众进行了半结构化的个人定性访谈。采用主题内容分析法对访谈进行分析。

结果

得出了四个类别和附加的子类别;对胚胎的不同看法需要谨慎、使用胚胎治疗帕金森病、以正确的方式做事、以及沟通、媒体和公众意见。总的来说,受访者对使用胚胎干细胞治疗 PD 持积极态度,但使用条件和具体要求受到限制。需要来自供体的知情同意,并且在处理胚胎时需要谨慎和敏感。

结论

使用多余的胚胎来治疗 PD 增加是比丢弃它们更好的选择,即使那些认为胚胎是“潜在生命”的人也是如此。参与者提出了一些允许在特定条件下进行治疗的使用胚胎的条件。即使胚胎最终将被丢弃,使用也需要捐赠夫妇的知情同意。

相似文献

4
Patients' views on using human embryonic stem cells to treat Parkinson's disease: an interview study.
BMC Med Ethics. 2022 Oct 19;23(1):102. doi: 10.1186/s12910-022-00840-6.
6
Donation of surplus frozen pre-embryos to research in Israel: underlying motivations.
Isr J Health Policy Res. 2016 Nov 5;5:25. doi: 10.1186/s13584-016-0085-4. eCollection 2016.
7
Attitudes towards embryo donation among infertile couples with frozen embryos.
Hum Reprod. 2013 Sep;28(9):2432-9. doi: 10.1093/humrep/det252. Epub 2013 Jun 11.

引用本文的文献

本文引用的文献

1
Donation of surplus frozen pre-embryos to research in Israel: underlying motivations.
Isr J Health Policy Res. 2016 Nov 5;5:25. doi: 10.1186/s13584-016-0085-4. eCollection 2016.
2
Concise Review: Human Embryonic Stem Cells-What Have We Done? What Are We Doing? Where Are We Going?
Stem Cells. 2017 Jan;35(1):17-25. doi: 10.1002/stem.2450. Epub 2016 Jul 17.
3
Factors associated with the donation and non-donation of embryos for research: a systematic review.
Hum Reprod Update. 2014 Sep-Oct;20(5):641-55. doi: 10.1093/humupd/dmu026. Epub 2014 Jun 6.
4
Attitudes toward embryo donation among staff at in vitro fertilization clinics.
Acta Obstet Gynecol Scand. 2014 Aug;93(8):765-70. doi: 10.1111/aogs.12407. Epub 2014 May 24.
5
Attitudes towards embryo donation in Swedish women and men of reproductive age.
Ups J Med Sci. 2013 Aug;118(3):187-95. doi: 10.3109/03009734.2013.808294. Epub 2013 Jun 20.
6
Asian immigrants to the United States are less likely to donate cryopreserved embryos for research use.
Fertil Steril. 2011 Apr;95(5):1672-6. doi: 10.1016/j.fertnstert.2011.01.123. Epub 2011 Feb 17.
8
Analysing and presenting qualitative data.
Br Dent J. 2008 Apr 26;204(8):429-32. doi: 10.1038/sj.bdj.2008.292.
9
Induction of pluripotent stem cells from adult human fibroblasts by defined factors.
Cell. 2007 Nov 30;131(5):861-72. doi: 10.1016/j.cell.2007.11.019.
10
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors.
Cell. 2006 Aug 25;126(4):663-76. doi: 10.1016/j.cell.2006.07.024. Epub 2006 Aug 10.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验