低剂量甲氨蝶呤治疗并发全血细胞减少症和卡氏肺孢子虫肺炎的类风湿关节炎。
Low dose methotrexate therapy for rheumatoid arthritis complicated by pancytopenia and Pneumocystis carinii pneumonia.
作者信息
Lang B, Riegel W, Peters T, Peter H H
机构信息
University of Freiburg Medical Center, Department of Rheumatology, Germany.
出版信息
J Rheumatol. 1991 Aug;18(8):1257-9.
PMID:1941837
Abstract
In a patient with rheumatoid arthritis pancytopenia and Pneumocystis carinii pneumonia occurred during low dose methotrexate therapy. This case emphasizes the potential development of opportunistic infections even with low dose methotrexate. Pneumocystis carinii pneumonia resembles methotrexate induced pneumonitis. Therefore opportunistic infections should be considered before a definite diagnosis of methotrexate induced pneumonitis is made.
摘要
一名类风湿关节炎患者在低剂量甲氨蝶呤治疗期间出现全血细胞减少和卡氏肺孢子虫肺炎。该病例强调了即使是低剂量甲氨蝶呤治疗也可能引发机会性感染。卡氏肺孢子虫肺炎与甲氨蝶呤诱发的肺炎相似。因此，在明确诊断为甲氨蝶呤诱发的肺炎之前，应考虑机会性感染。
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