用热解质谱法对化脓性链球菌进行分型
Typing of Streptococcus pyogenes by pyrolysis mass spectrometry.
作者信息
Magee J T, Hindmarch J M, Nicol C D
机构信息
Department of Microbiology, Children's Hospital, Sheffield.
出版信息
J Med Microbiol. 1991 Nov;35(5):304-6. doi: 10.1099/00222615-35-5-304.
Strains of Streptococcus pyogenes from an outbreak in an oncology ward (13) and routine isolates from sporadic cases (6) were examined blind by pyrolysis mass spectrometry (Py-MS), extending previous work on epidemiological typing. This outbreak appeared more complex than one reported previously, but Py-MS and conventional typing results were in complete agreement. The results confirm the potential of Py-MS as a rapid method for identification at strain level in studies of cross infection.
对来自肿瘤病房一次暴发的13株化脓性链球菌菌株以及散发病例的6株常规分离菌株，采用热解质谱法（Py-MS）进行了盲法检测，以扩展先前关于流行病学分型的研究。此次暴发似乎比之前报道的一次更为复杂，但热解质谱法和传统分型结果完全一致。结果证实了热解质谱法作为交叉感染研究中菌株水平快速鉴定方法的潜力。
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