Fujiyama J
Department of Dermatology, Yamaguchi University School of Medicine.
Nihon Hifuka Gakkai Zasshi. 1991 Jun;101(7):707-18.
The human adult intraepidermal eccrine sweat duct (IESD) were studied by the transmission electron microscope. The formation of the intracytoplasmic cavities was demonstrated in the luminal cell of the adult IESD, and the relation between the intracytoplasmic cavities and the IESD formation was as follows. On the eccrine sweat duct ridge, these intracytoplasmic cavities enlarged, broke through the cell membrane and coalesced into the intercellular lumen. Furthermore, several intercellular lumina were merged into the intraepidermal ductal lumen. In the lower to upper squamous layers, small intracytoplasmic cavities were formed around the intraepidermal duct and were fused into the duct. Simultaneously, the contents of the intracytoplasmic cavities were discharged into the ductal lumen. Intracytoplasmic cavities in these layers were ordinarily formed and concerned in not only the reconstruction of the duct but also the secretory function. The intracytoplasmic cavities were surrounded with the same microvilli as lined the intraepidermal ductal lumen. Many clear vesicles (about 0.1 microns in diameter) were observed near the intracytoplasmic cavities, but multivesicular dense bodies (MDB) were not seen near the cavities. These vesicles were considered to participate in the formation of the intracytoplasmic cavities.
利用透射电子显微镜对成人表皮内小汗腺导管（IESD）进行了研究。在成人IESD的管腔细胞中证实了胞质内小腔的形成，胞质内小腔与IESD形成的关系如下。在小汗腺导管嵴上，这些胞质内小腔扩大，突破细胞膜并融合形成细胞间腔。此外，几个细胞间腔融合形成表皮内导管腔。在鳞状上皮的下层到上层，围绕表皮内导管形成小的胞质内小腔，并融合到导管中。同时，胞质内小腔的内容物排入导管腔。这些层中的胞质内小腔通常形成，不仅与导管的重建有关，还与分泌功能有关。胞质内小腔被与表皮内导管腔内衬相同的微绒毛所包围。在胞质内小腔附近观察到许多透明小泡（直径约0.1微米），但在小腔附近未见多囊致密体（MDB）。这些小泡被认为参与了胞质内小腔的形成。
