Caldeira Roberta L, Jannotti-Passos Liana K, Carvalho Omar S
Laboratório de Helmintologia e Malacologia Médica, Centro de Pesquisa René Rachou/Fiocruz, Minas Gerais, Brazil.
Acta Trop. 2009 Jul;111(1):1-6. doi: 10.1016/j.actatropica.2009.02.004. Epub 2009 Mar 3.
The three vector species of Schistosoma mansoni in Brazil, Biomphalaria glabrata, B. tenagophila and B. straminea show different susceptibility levels to the trematode besides a wide geographical distribution. The identification of such molluscs is important to further understand the disease epidemiology. Considering the fact that morphological identification may become difficult or even impossible under particular circumstances, the use of molecular-based methods have permitted the generation of more consistent information concerning the population structure of Biomphalaria furthering knowledge on taxonomy and diagnosis of infection. We have developed methodologies in order to provide simultaneous species identification of the intermediate host and diagnosis of infection with S. mansoni.
巴西曼氏血吸虫的三种病媒螺类,即光滑双脐螺、嗜多双脐螺和稻草双脐螺,除了分布广泛外,对这种吸虫还表现出不同的易感性水平。识别这些软体动物对于进一步了解疾病流行病学很重要。鉴于在某些特定情况下形态学识别可能变得困难甚至无法进行,基于分子的方法的使用使得能够生成关于双脐螺种群结构的更一致信息,从而加深对分类学和感染诊断的认识。我们已经开发出了一些方法,以便能够同时对中间宿主进行物种识别并诊断曼氏血吸虫感染情况。