Hougaard Karin S, Hannerz Harald, Feveile Helene, Bonde Jens P
National Research Centre for the Working Environment, DK-2100 Copenhagen, Denmark.
Reprod Toxicol. 2009 Apr;27(2):186-9. doi: 10.1016/j.reprotox.2009.01.003. Epub 2009 Jan 21.
Several plastic chemicals adversely affect reproductive ability. This study examined the possible association between employment in the plastics industry and infertility. Dynamic cohorts of economically active women and men were followed for hospital contacts due to infertility in the Danish Occupational Hospitalisation Register, from 1995 to 2005. A person was considered to be at increased risk in a particular year if plastic work was the main occupation in the previous year. Analyses were standardized according to county, socio-economic group, year and age. 107 cases of treatment for female infertility were observed among female plastic workers, as opposed to an expected 87.15 cases, i.e. relative risk was 1.23 (95% CI: 1.01-1.48). For male workers the numbers were 41 respectively 49.9 cases, with relative risk being 0.82 (95% CI: 0.59-1.11). The increased incidence of infertility treatment in female plastics workers motivates more specific studies of reproductive occupational health in the plastics industry.
几种塑料化学品会对生殖能力产生不利影响。本研究调查了从事塑料行业工作与不孕不育之间可能存在的关联。1995年至2005年期间，在丹麦职业住院登记处，对有经济活动的女性和男性动态队列因不孕不育而住院的情况进行了跟踪调查。如果前一年主要从事塑料相关工作，那么此人在特定年份被视为风险增加。分析按县、社会经济群体、年份和年龄进行了标准化处理。在女性塑料行业工作者中，观察到107例女性不孕不育治疗病例，而预期为87.15例，即相对风险为1.23（95%置信区间：1.01 - 1.48）。男性工作者的病例数分别为41例和49.9例，相对风险为0.82（95%置信区间：0.59 - 1.11）。女性塑料行业工作者中不孕不育治疗发病率的增加促使对塑料行业生殖职业健康进行更具体的研究。
