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韩国职业女性的流产率及不良妊娠结局:一项横断面研究。

Prevalence of abortion and adverse pregnancy outcomes among working women in Korea: A cross-sectional study.

作者信息

Park Chulyong, Kang Mo-Yeol, Kim Dohyung, Park Jaechan, Eom Huisu, Kim Eun-A

机构信息

Occupational Safety and Health Research Institute, Korea Occupational Safety and Health Agency, Ulsan, Korea.

Department of Occupational and Environmental Medicine, Sungkyunkwan University School of Medicine, Seoul, Korea.

出版信息

PLoS One. 2017 Aug 29;12(8):e0182341. doi: 10.1371/journal.pone.0182341. eCollection 2017.

Abstract

OBJECTIVES

To investigate incidence and distribution of major adverse reproductive health problems related to various kinds of industries in Korea and to compare risks for major reproductive outcomes to assess maternal health in working and non-working women.

METHODS

We requested claim data from the Korean National Health Insurance. We defined reference groups as (1) non-working women and (2) workers in the education field. Women working in each industry were compared with reference groups regarding rates of miscarriage, threatened abortion, preterm labor, and intrauterine growth restriction. Logistic regression was used for multivariate analysis, and age and income adjustment was performed.

RESULTS

The percentages of all adverse obstetric outcomes were higher in working women than in non-working women. Working women had higher and statistically significant adjusted odds ratios (ORs) for miscarriage in 18 of the 21 industries. The age and income-adjusted OR for miscarriage for all working women was 1.26 (95% confidence interval, 1.23-1.28). Business facilities management and business support services, manufacturing, human health and social work activities, wholesale and retail trade, and professional, scientific, and technical activities were major industries with higher adjusted ORs for adverse obstetric outcomes.

CONCLUSIONS

We confirmed that compared to non-working women, working women have a higher risk for adverse pregnancy outcomes. Thus, adverse pregnancy outcomes such as threatened abortion, preterm labor, and intrauterine growth restriction may be associated with working status. This exploratory study identified several industries where in-depth studies are required in future to improve occupational safety in women of reproductive age.

摘要

目的

调查韩国各类行业中与主要不良生殖健康问题相关的发病率和分布情况,并比较主要生殖结局的风险,以评估在职和非在职女性的孕产妇健康状况。

方法

我们向韩国国民健康保险申请理赔数据。我们将参照组定义为:(1)非在职女性和(2)教育领域的工作者。将各行业的在职女性与参照组在流产、先兆流产、早产和胎儿宫内生长受限发生率方面进行比较。采用逻辑回归进行多变量分析,并进行年龄和收入调整。

结果

在职女性中所有不良产科结局的百分比均高于非在职女性。在21个行业中的18个行业,在职女性流产的调整优势比(OR)更高且具有统计学意义。所有在职女性流产的年龄和收入调整后的OR为1.26(95%置信区间,1.23 - 1.28)。商业设施管理与商业支持服务、制造业、人类健康和社会工作活动、批发和零售贸易以及专业、科学和技术活动是不良产科结局调整后OR较高的主要行业。

结论

我们证实,与非在职女性相比,在职女性不良妊娠结局的风险更高。因此,先兆流产、早产和胎儿宫内生长受限等不良妊娠结局可能与工作状态有关。这项探索性研究确定了几个行业,未来需要对这些行业进行深入研究,以改善育龄女性的职业安全。

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