Velasco-Garcia M N
Department of Chemistry and Analytical Sciences, Faculty of Science, The Open University, Walton Hall, Milton Keynes MK7 6AA, United Kingdom.
Semin Cell Dev Biol. 2009 Feb;20(1):27-33. doi: 10.1016/j.semcdb.2009.01.013. Epub 2009 Feb 3.
New approaches are required to understand the complex processes taking place in the smallest unit of life. Recent years have seen an increasing activity in the use of optical devices and techniques for the investigation of the properties of single cells and also populations of cells including cell to cell communication. This article reviews relevant optical technologies to date as well as new advances in biosensor development, and goes on to explore reported applications in detection of biotargets and cellular signalling pathways inside individual living cells.
需要新的方法来理解生命最小单位中发生的复杂过程。近年来，人们越来越多地利用光学设备和技术来研究单细胞以及包括细胞间通讯在内的细胞群体的特性。本文回顾了迄今为止相关的光学技术以及生物传感器开发方面的新进展，并继续探讨了在检测单个活细胞内的生物靶点和细胞信号通路方面的报道应用。
