Shakov Rada, DePasquale Joseph R, Elfarra Hossam, Spira Robert S
Division of Gastroenterology, St. Michael's Medical Center, 268 Martin Luther King Boulevard, Newark, NJ 07102, USA.
Ann Clin Lab Sci. 2009 Spring;39(2):167-75.
Autoimmune pancreatitis (AuP) is a chronic pancreatic inflammation secondary to an underlying autoimmune mechanism. After early reports of a particular type of pancreatitis associated with hypergammaglobulinemia, others asserted that there is an autoimmune mechanism involved in some patients with chronic pancreatitis. In 1995 AuP was first described as a distinct clinical entity. Since then, there have been many documented cases of AuP in Japan, and now, perhaps due to increased awareness, more cases are being reported in Europe and the United States. Herein we present our experience with 3 cases of AuP and we review the relevant literature. These 3 cases demonstrate the difficulties that exist in making the diagnosis of AuP and the impact that the diagnosis can have on patient management.
自身免疫性胰腺炎（AuP）是一种继发于潜在自身免疫机制的慢性胰腺炎症。在早期报道了一种与高球蛋白血症相关的特殊类型胰腺炎后，其他人断言，一些慢性胰腺炎患者存在自身免疫机制。1995年，AuP首次被描述为一种独特的临床实体。从那时起，日本有许多记录在案的AuP病例，现在，也许是由于认识的提高，欧洲和美国报告的病例更多。在此，我们介绍我们对3例AuP的经验，并回顾相关文献。这3例病例展示了在诊断AuP时存在的困难以及该诊断对患者管理可能产生的影响。
