Ratnikova L I
Klin Med (Mosk). 1991 Jul;69(7):89-90.
The trial entered 66 patients with recurrent erysipelas treated conventionally with addition of either immunostimulator bemitil (0.25-0.5 g/day orally for 5-7 days) or placebo. The bemitil group was free of intoxication symptoms and local manifestations, discharged from hospital sooner than the controls. Therapeutic efficacy of bemitil is due to its promotion of mononuclear phagocytes function which acts as an essential mechanism of antibacterial defence activation in patients with recurrent erysipelas.
该试验纳入了66例复发性丹毒患者,这些患者接受常规治疗,并添加免疫刺激剂贝米替尔(口服0.25 - 0.5克/天,持续5 - 7天)或安慰剂。贝米替尔组无中毒症状和局部表现,比对照组更早出院。贝米替尔的治疗效果归因于其促进单核吞噬细胞功能,这是复发性丹毒患者抗菌防御激活的重要机制。