Biffl Walter L, Kaups Krista L, Cothren C Clay, Brasel Karen J, Dicker Rochelle A, Bullard M Kelley, Haan James M, Jurkovich Gregory J, Harrison Paul, Moore Forrest O, Schreiber Martin, Knudson M Margaret, Moore Ernest E
Department of Surgery, Denver Health Medical Center/University of Colorado-Denver, Denver, Colorado 80204-4507, USA.
J Trauma. 2009 May;66(5):1294-301. doi: 10.1097/TA.0b013e31819dc688.
The optimal management of hemodynamically stable, asymptomatic patients with anterior abdominal stab wounds (AASWs) remains controversial. The goal is to identify and treat injuries in a safe, cost-effective manner. Common evaluation strategies include local wound exploration (LWE)/diagnostic peritoneal lavage (DPL), serial clinical assessments (SCAs), and computed tomography (CT) imaging. The purpose of this multicenter study was to evaluate the clinical course of patients managed by the various strategies, to determine whether there are differences in associated nontherapeutic laparotomy (NONTHER LAP), emergency department (ED) discharge, or complication rates.
A multicenter, Institutional Review Board-approved study enrolled patients with AASWs. Management was individualized according to surgeon/institutional protocols. Data on the presentation, evaluation, and clinical course were recorded prospectively.
Three hundred fifty-nine patients were studied. Eighty-one had indications for immediate LAP, of which 84% were therapeutic. ED D/C was facilitated by LWE, CT, and DPL in 23%, 21%, and 16% of patients, respectively. On the other hand, LAP based on abnormalities on LWE, CT, and DPL were NONTHER in 57%, 24%, and 31% of patients, respectively. Twelve percent of patients selected for SCA ultimately had LAP (33% were NONTHER); there was no apparent morbidity due to delay in intervention.
Shock, evisceration, and peritonitis warrant immediate LAP after AASW. Patients without these findings can be safely observed for signs or symptoms of bleeding or hollow viscus injury. To limit the number of hospital admissions, we propose a uniform strategy using LWE to ascertain the depth of penetration; the patient may be safely discharged in the absence of peritoneal violation. Peritoneal penetration, absent evidence of ongoing hemorrhage or hollow viscus injury, should not be considered an indication for LAP, but rather an indication for admission for SCAs. We suggest that a prospective multicenter trial be performed to document the safety and cost-effectiveness of such an approach.
对于血流动力学稳定、无症状的前腹壁刺伤(AASW)患者的最佳处理方法仍存在争议。目标是以安全且具有成本效益的方式识别并治疗损伤。常见的评估策略包括局部伤口探查(LWE)/诊断性腹腔灌洗(DPL)、系列临床评估(SCA)以及计算机断层扫描(CT)成像。这项多中心研究的目的是评估采用各种策略处理的患者的临床病程,确定在相关的非治疗性剖腹手术(NONTHER LAP)、急诊科(ED)出院情况或并发症发生率方面是否存在差异。
一项经机构审查委员会批准的多中心研究纳入了AASW患者。处理方式根据外科医生/机构的方案进行个体化。前瞻性记录有关临床表现、评估及临床病程的数据。
共研究了359例患者。81例有立即进行剖腹手术的指征,其中84%为治疗性手术。LWE、CT和DPL分别使23%、21%和16%的患者在急诊科得以出院。另一方面,基于LWE、CT和DPL异常而进行的剖腹手术,分别有57%、24%和31%的患者为非治疗性手术。选择SCA的患者中有12%最终进行了剖腹手术(33%为非治疗性手术);未因干预延迟而出现明显的发病率。
AASW后出现休克、脏器外露和腹膜炎需要立即进行剖腹手术。没有这些表现的患者可以安全地观察有无出血或中空脏器损伤的体征或症状。为了限制住院人数,我们提出一种统一的策略,即使用LWE确定穿透深度;若无腹膜侵犯,患者可安全出院。腹膜穿透,若没有持续出血或中空脏器损伤的证据,不应被视为剖腹手术的指征,而应是入院进行SCA的指征。我们建议进行一项前瞻性多中心试验,以证明这种方法的安全性和成本效益。